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Development of retinoblastoma services in Zimbabwe
Zimbabwe recognised the need for a paediatric ophthalmology service almost 20 years ago. The economic uncertainty in the country made it difficult to secure financial support, so initial funding came through local donors. Equipment – including vision charts, ophthalmoscopes and...Medical and eye health teams defy odds to deliver treatments for trachoma in Ethiopia, but millions worldwide risk return of disease amid UK aid cuts
Ophthalmologists, nurses, and eye health workers in Ethiopia defied the odds to treat millions with trachoma-fighting antibiotics and surgeries - despite cuts to UK Aid assistance threatening eye care. This World Neglected Tropical Diseases Day Orbis, the international eye care...The screening and treatment of retinopathy of prematurity
A male child is born at 31 weeks and requires 100% oxygen supplementation with intensive care. What would be the ophthalmic management of this child? In the first instance, it will be useful to know the screening criteria and protocol....Things I’d tell my medical school self, had I known my first year on the job would be during a global pandemic
In a conversation with his younger self, a foundation doctor reflects on the contrast between his expectations of medicine at university and the reality of working during the coronavirus pandemic. Every doctor arrives at medical school with nervous anticipation, yet...Feb/Mar 2014 Quiz 2
History A 65-year-old lady presented with a ten year history of nonspecific visual disturbance and mild symptoms of dry eyes. Questioning revealed progressive nyctalopia. Previous medical history of note included Crohn’s disease requiring two bowel resections including small intestine. Figure...
Allergic eyelid dermatitis
This is a retrospective 12 year review of 61 patients diagnosed with periocular allergic dermatitis. The average age was 66 years, with 74% being female. The commonest indications for referral were epiphora, ectropion and blepharitis; and the main symptoms were...
Transfected RPE cells inhibit AMD in rats
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...
Effect of topical diclofenac on postoperative PRK pain: RCT
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Aqueous humour cytokine levels in PCV and nAMD
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Combined anti-VEGF and PDT for wet AMD
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Four year outcomes of macular degeneration treated with ranibizumab
The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...
