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3491 results found

Investigation of PAX7 positive satellite cells in extraocular muscle surgery

PAX7 is a transcription factor and is expressed in non-active and activated satellite cells. It is needed for muscle progenitor function, survival and expansion. This study investigates the effect of recession/resection surgery on PAX7-positive satellite cells in extraocular muscles of...

The most memorable patient encounters and what they taught me

In ophthalmology, some encounters blend quietly into the rhythm of clinic. Others stay with us, shaping how we practice and who we become as clinicians. These moments become the unexpected teachers of our training. They are subtle yet leave a...

Mydrin-P microdrops vs mydrin-P standard drops for ROP examination

This was a non-inferiority prospective randomised controlled trial to compare efficacy and safety of microdrops over standard dose mydrin-P in retinopathy of prematurity (ROP) screening, and to determine optimal time for eye examination after administration of drops. The trial included...

The Art of Refractive Cataract Surgery

The Art of Refractive Cataract Surgery is a structured and clinically focused textbook aimed at ophthalmology residents, fellows and surgeons seeking a systematic introduction to refractive cataract surgery. Content is presented in a clear format, with concise sections, and effective...

Systematic review investigating the time taken for corneal stabilisation following contact lens cessation

A systematic literature review of 15 studies (13 prospective, 1 retrospective and 1 case observational case series) to assess corneal stabilisation post-contact lens (CL) cessation by using corneal imaging techniques. The included studies reported stabilisation of corneal parameters as follows;...

Systematic review of BTA vs surgery for partially accommodative esotropia

The authors conducted a systematic review and meta-analysis to evaluate the efficacy of botulinum toxin A (BTA) vs bilateral medial rectus muscle recessions for management of partially accommodative esotropia. They included 4 eligible studies with a total of 521 patients....

Infantile exotropia surgical outcomes

This study investigates the success rate and dose response of bilateral lateral rectus muscle recessions (BLL) and bilateral lateral rectus muscle recessions plus unilateral medial rectus resection (LMR) on basic type infantile exotropia of 20–45PD. This was a retrospective review...

Associated ocular and systemic disease in congenital cataract

The authors examined the impact of accompanying systemic diseases on surgical planning and the postoperative period in patients undergoing congenital cataract surgery. This was a retrospective study over 2010–2024 of 142 patients (239 eyes): 75 females and 67 males. 45...

Tocilizumab effectiveness in paediatric non-infectious uveitis: data from the International AIDA Network Registries on ocular inflammatory disorders

Medical records of 15 paediatric patients (onset before age of 16) affected by refractory non-infectious uveitis (NIU) and treated by tocilizumab (TCZ) were reviewed. Data were extracted from the international AIDA Network for uveitis registry and Behcet’s disease registries. They...

Clinical characteristics and visual outcome of patients with macular pseudohole

This is a retrospective study of consecutive patients with macular pseudohole (MPH) who had vitrectomy and were followed for at least 6 months postoperatively. MPH was diagnosed based on spectral-domain optical coherence tomography (OCT) findings. 76 eyes of 75 patients...

Eye research: where next?

Eye research in the UK is underfunded relative to other areas of medical research and general awareness of sight loss and its prevention remains poor, messages that were reinforced in presentations and discussions during a recent research summit meeting in...

Retinoblastoma – the challenges of a rare cancer and the role of international partnerships

Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...