You searched for "therapeutics"

367 results found

Advances in the understanding, diagnostic and treatment of keratoconus

*Joint first authors Keratoconus is a bilateral and asymmetric eye condition in which the cornea’s structure is affected and thinned, causing a cone-shaped bulge to develop. This results in progressive loss of vision and impairs the ability of the eye...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Gene therapy: perspectives from young adults with Leber’s congenital amaurosis

The authors present their telephone survey data of 10 patients with a mean age of 24.4 years regarding their opinion on gene therapy for their Leber’s congenital amaurosis. Patients were recruited at the Hospital for Sick Children, Toronto. Of the...

Latest NHS plan to modernise primary care misses an opportunity

Government announces drive to digitise GP phonelines and offer greater options in patient access to care in dentistry and pharmacy, but does not capitalise on opportunities to improve patient experiences closer to home or address IT connectivity issues holding back optometry services.

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy, offering new ways for future therapies to target this common, age-related cause of visual loss. In a landmark study, researchers supported by NIHR Moorfields Biomedical Research Centre, have identified...

Is thrombolytic treatment warranted for central retinal artery occlusion?

Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke which results in severe visual loss. Acute CRAO is equivalent to a brain acute ischaemic stroke (AIS), as the obstruction of the central retinal artery (CRA) causes end-organ...

BMLA 2023 Annual Conference & Educational Courses

Navroz Singh (far right) with Nirmal and Vasant Oswal (second and third left) and the other recipients of the Vasant and Nirmal Oswal Trainee Scholarship. Navroz Singh, core surgical trainee at Kings College NHS Trust. This year’s British Medical Laser...

BMLA Annual Conference & Educational Courses

Navroz Singh, core surgical trainee at Kings College NHS Trust. This year’s British Medical Laser Association (BMLA) annual conference was held over three days in a beautiful venue overlooking a sunny Cardiff Bay. It was attended by individuals hailing from...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...

Use of orthoK for myopia treatment

This article provides an updated literature review on the orthkeratology effect on myopia progression considering outcome measures, potential effect modifiers, mechanisms and current prescription concerns. The discussion centres on the extent of slowed myopia progression, mechanisms, safety concerns and comparisons...

A to Z of X-linked retinopathies

This review article provides an excellent summary of X-linked retinopathies and the corresponding genotype and clinical features. The authors provide a comprehensive overview of each condition in terms of its pathogenesis, clinical features, imaging findings, electrophysiology changes and any current...

Bacterial keratitis through the window of the known unknowns

This review article provides an up-to-date summary of current challenges in research and management of bacterial keratitis. The authors highlight that there is no current agreement on the criteria that should define bacterial keratitis; the role of investigation is unclear,...