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2692 results found

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

Pars plana vitrectomy for vitreomacular traction syndrome

This paper presents a meta-analysis and systematic review of the safety and efficacy of vitrectomy for vitreomacular traction (VMT), based on 21 eligible articles from 460 identified. A strength of this study is that it provided pooled analysis across a...

CD40L activation of human RPE cells

Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Prognostic information for PRP-naive patients

The Diabetic Retinopathy Study group demonstrated that pan retinal laser photocoagulation (PRP) reduces severe vision loss by up to 50% in cases of proliferative diabetic retinopathy (PDR). The authors of this current study aimed to provide information for laser naive...

Macular thickness and visual fields

The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...

Aug/Sep 2015 Quiz 2

History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Ultra-widefield fundus autofluorescence

The authors assessed the ease and utility of ultra-widefield fundus autofluorescence (UWF-FAF) in detecting suspected inherited retinal disease in children who were difficult to examine. They aimed to assess the sensitivity of UWF-FAF and UWF-CF (colour fundus) photography and clinical...

Cataract extraction and microperimetry

In this study, the authors assessed retinal sensitivity before and after cataract extraction, in an effort to understand how lens opacities may affect microperimetry results in glaucoma and macular diseases. Thirty patients awaiting cataract extraction were examined and their lens...

Visual outcomes after surgery for primary RRD in era of microincision vitrectomy

This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...