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Congenital and paediatric cataract: Advances in diagnosis and management
Congenital and paediatric cataracts are relatively rare, although prevalence varies significantly between countries, influenced by factors such as nutrition, immunisation policy and population genetics [1]. In the UK, around 3–4 of every 10,000 babies are born with cataracts. It’s a...
Use of Leflunomide as a treatment for paediatric chronic uveitis
Leflunomide is a disease modifying anti-rheumatic drug approved for treatment of rheumatoid arthritis and psoriatic arthritis in adult patients. This study reports five illustrative case reports of children using Leflunomide as an adjunct treatment with anti-tumour necrosis factor (TNF) agents...
A practical approach to uveitis screening in children with juvenile idiopathic arthritis
The multinational Interdisciplinary Working Group for Uveitis in Children consists of 10 paediatric rheumatologists and five paediatric ophthalmologists with expertise in paediatric uveitis. They identified a simplified screening recommendation to enable local eyecare professionals (ECPs) to screen children with juvenile...Refined glaucoma referral practice offers prospect of improved capacity and expanded role for primary eye care professionals
Glaucoma is the most frequent cause of irreversible blindness worldwide and the second leading cause of blindness in the UK [1,2]. The global prevalence of glaucoma in 2010 was approximately 3.5% for people aged 40-80 years, according to Jonas et...Innovations in ophthalmology: what can the innovations of the past teach us about tomorrow?
BUOS Prize Essay – 2nd prize winner for 2013 submissions Introduction An essay titled Innovations in Ophthalmology might choose to focus on the history; from cataract couching to femtosecond lasers, ophthalmology has had no shortage of topics worthy of discussion....Impact of Eye Health Surveys and Partnerships in The Gambia
This article brings together the three national eye health surveys that have been undertaken in The Gambia between 1986 and 2019 and the impact that the results have had nationally and internationally. In it we describe the long-term capacity-strengthening for...Forward looking practices to plan for 5 years at 100% Optical
The OSA is urging practices to adopt a forward-thinking approach and to make investment decisions for a five-year business plan, as the industry and profession meet at 100% Optical 24-26 February.Refraction planning in cataract: avoid creating an unhappy patient
“It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has.” William Osler The focus of this paper is the prevention of an unhappy patient following cataract...NYU Langone Health performs world’s first whole-eye & partial-face transplant
Landmark whole-eye transplant is a major paradigm shift for potential vision therapies.
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
