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3550 results found

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

425,000 NHS patients use online GP registration service in first year

More than 425,000 patients have used a new national online service to register with a GP in its first year.

Cyclosporine A and pterygium fibroblasts

The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...

Data update for leading causes of CVI in England and Wales

In this article the authors present an epidemiological update, based on certifiable visual impairment (CVI) registration for figures for sight impairment (SI) in England and Wales from the last report of 2007-2008 to the current data for April 2012 to...

Simultaneous surgery for ptosis and strabismus

The authors present the surgical management of congenital ptosis and coexistent strabismus at one centre for a follow-up period of >2 years. This was a retrospective review of 10 patients (17 eyes); nine males. Intermittent exotropia was present in three...

Clinical features of ocular syphilis

The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....

Neurogenic palsy due to COVID-19

The authors aimed to identify cases of neurogenic palsy in the presence of Covid-19 and document the patient characteristics, type of palsy and possible aetiologies. Case reports and case series were included in the search. Twenty-three articles were included with...

Long-term incidence and survival trends in retinoblastoma in the USA

The authors present a retrospective observational study of 5730 patients diagnosed with retinoblastoma between 1996 and 2018. Data on demographics, age at diagnosis, treatment and survival were extracted from national registries with coverage of 99% of the population of the...

Surgical outcome for cyclic strabismus

The aim of this study was to report the outcome of surgical treatment in a series of seven cases of paediatric cyclic strabismus. This was a retrospective study of children with surgical treatment for the manifest cyclic deviation. Six children...

Prevalence of anisometropia and associated factors in Iranian children

The aim of this study was to determine the prevalence of anisometropia and the associated demographic and biometric risk factors in children. Data were taken from the first phase of the Shahroud Schoolchildren Eye Cohort cross-sectional study. From this phase,...

Second sight: Ian McKinley

I have always been captivated by a true-life story demonstrating the human spirit of triumph over adversity. For me, one of the most memorable sportsmen overcoming an injury has always been the mountaineer Joe Simpson and his tale of survival...