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Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Abducens nerve palsy following surgical correction of craniosynostosis

The authors present two cases of unilateral abducens palsy secondary to a recent trans-sutural distraction osteogenesis (TSuDO) operation for craniosynostosis. The basic principle of the TSuDO procedure is described as dissection and distraction of the prematurely fused sutures. This complication...

Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

Features and outcomes of pulled-in-two syndrome

Pulled-in-two (PIT) syndrome is a sudden rupture of the extraocular muscle during strabismus surgery, typically with minimal tension intraoperatively without excessive force. This is a rare occurrence and this study reports cases from a single centre over a seven-year period....

Global Experts Unite: Visionary Horizons Sets the Stage for the Future of Ophthalmology

Heidelberg Engineering, as part of EssilorLuxottica, marked a milestone in global eyecare innovation with the inaugural Visionary Horizons symposium — the first event of its kind showcasing Heidelberg’s pioneering innovation and expertise as a driving force within EssilorLuxottica’s technological and...

Just sign here: the intricacies of consent in the post-Montgomery era

The consent process is a vital part of the patient pathway and is far more than just getting the patient to sign on the dotted line. In my work in litigation I often see issues around informed consent resulting in...

Accelerated (9mW/cm2) corneal collagen cross-linking for keratoconus

This is one of many studies published / to be published on corneal collagen cross-linking that has a treatment time of 10 minutes compared to the previous Dresden protocol of 30 minutes to halt progression of keratoconus. Much has changed...

Inhibiting high-risk corneal allografts

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...

Effect of rebubbling after DMEK

This study objectively evaluated the impact of rebubbling on postoperative corneal clarity and endothelial cell loss (ELD) after DMEK. This was a retrospective analysis of 132 consecutive DMEK cases performed for Fuchs endothelial dystrophy or pseudophakic bullous keratopathy. Patients were...

Differences of the anterior segment parameters in children with Down syndrome

This cross-sectional study was designed in order to demonstrate the differences in anterior segment parameters in children with trisomy 21. This is important as it may impact on surgical planning when undertaking procedures in the anterior segment such as corneal...

Outcomes of corneal collagen crosslinking (CXL) in pseudophakic bullous keratopathy (PBK)

This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...

Evaluation of keratometry with a novel colour LED corneal topographer

The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...