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Adjunct amniotic membrane during enucleation for retinoblastoma to prevent implant exposure
Amniotic membrane (AM) has potential for treatment of retinoblastoma (RB) patients with contracted sockets after enucleation. The authors present their experience of AM with enucleation for patients with RB after chemotherapy in this retrospective study of 100 eyes of 107...Redeployment during the COVID-19 pandemic: personal accounts from four ophthalmology trainees
We once believed that the coronavirus would not penetrate the safe confines of the United Kingdom, like so many outbreaks before this. Once the news came that this pandemic descended into our hospitals, the anxieties about redeployment began. Many of...Acute macular neuroretinopathy
Acute macular neuroretinopathy (AMN) is a rare condition that typically affects young women and presents with photopsia and paracentral scotomata [1]. We describe a case of severe acute macular neuroretinopathy, following Covid-19 infection. A 30-year-old woman presented to the urgent...Contemporary glaucoma therapy: spoilt for choice
The goal of glaucoma management is to prevent visual loss and disease progression in the patient’s lifetime through effective lowering of intraocular pressure (IOP), the primary modifiable risk factor in glaucoma. Sustained and consistent IOP reduction is key to halting...The invisible touch: a VISION 2020 LINK with Indonesia
Indonesia’s population, the world’s fourth largest, is spread across 6,000 inhabited islands. Whilst some areas (e.g. Kalimantan, Papua) are relatively sparsely populated, Java is the world’s most densely populated island, with twice the population of the UK in half the...
Steroid implants in the treatment of post-epiretinal membrane peel macular oedema
This is a retrospective review of 39 eyes of 37 patients treated with Ozurdex® (intravitreal dexamethasone implant) for persistent post-operative cystoid macular oedema (CMO) following vitrectomy and idiopathic epiretinal membrane (ERM) peeling. The 0.7mg implant was injected in each eye...
Transfected RPE cells inhibit AMD in rats
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...
Effect of topical diclofenac on postoperative PRK pain: RCT
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Aqueous humour cytokine levels in PCV and nAMD
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Intracameral bevacizumab as an adjunct to trabeculectomy
This is a 12-month, prospective, randomised, double-masked, placebo-controlled trial of patients who were not controlled medically with open angle glaucoma and scheduled for a primary trabeculectomy. Patients were recruited and randomised during the period between April 2009 and November 2010....
Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients
For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...
