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Gender and ethnicity related differences in optic nerve head
The authors investigated the effect of ethnicity and gender on optic nerve head morphology comparing Indian and Caucasian males and females. The optic nerve head was investigated using spectral-domain optic coherence tomography (SD-OCT). Results showed that disc and rim areas...
Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide
X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...
Visual fields and OCT in hydroxychloroquine retinopathy
It has been recommended that patients on hydroxychloroquine be monitored regularly for retinopathy. However, there has not been an agreement as to the best screening test for hydroxychloroquine toxicity, which may include visual fields (VF), fundus autofluorescence, spectral domain optical...
Spectral domain OCT vs. confocal scanning laser ophthalmoscope in measuring RNFL thickness
The aim of this prospective study was to compare the retinal nerve fibre layer thickness (RNFL) measurements obtained from the Cirrus optical coherence tomography (spectral domain OCT) with the Heidelberg Retinal Tomograph 3 (HRT3, confocal scanning laser ophthalmoscope). Eighty-eight normal...
Avastin vs. Volon A for diabetic macular oedema
This prospective randomised interventional clinical trial compared 30 diabetic patients with macular oedema treated with either intravitreal injections of bevacizumab (Avastin) or triamcinolone (Volon A). One group initially received three injections of 2.5 mg Avastin in monthly intervals whilst the...
Microperimetry of subretinal drusenoid deposits
Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...
Macular oedema after cataract surgery in diabetic patients
The authors describe a multi-centre prospective observational study of 293 participants that underwent cataract surgery who all had diabetic retinopathy without definite central-involved macular oedema. Forty-five clinical sites took part throughout the United States. Patients were eligible if there was...
Radiation maculopathy
This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...
OCT in microtropia
The aim of this study was to assess whether OCT could be useful in detecting and documenting fixation in children with microtropia. The study used spectral domain OCT (Cirrus) in 15 patients (10 female, five male) and 10 control eyes....
Retinal microvasculature in amblyopic eyes
This study evaluated and compared measurements of macular vessel density and foveal avascular zone using optical coherence tomography (OCT) angiography in amblyopia eyes and age-matched controls to determine whether results are in agreement with previous studies. This was a cross...
Handheld OCT in children with Down’s syndrome
This article investigated the use of handheld optical coherence tomography (OCT) in children with Down’s syndrome. Fourteen children were recruited to the study with a mean age of 6 years and 10 months with 57% male. All patients were dilated....
