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The compendium to clinical evidence in DMO treatment
This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these...
Progression of macular atrophy in Stargardt disease
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Is thrombolytic treatment warranted for central retinal artery occlusion?
Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke which results in severe visual loss. Acute CRAO is equivalent to a brain acute ischaemic stroke (AIS), as the obstruction of the central retinal artery (CRA) causes end-organ...
Use of oral fluorescein angiography in a paediatric population
The authors report a retrospective records review of all patients who received an oral ultrawide fluorescein angiography (FA) over a 42-month period at a single children’s hospital. Data were extracted from the records including indication for FA, adverse events, pauses...
Portable vision reading device shows promise for low vision after brain injury
The authors report a small sample cohort study evaluating the impact of a portable vision reading device (OrCam Read) on vision-related quality-of-life and independent functional status in patients with low vision due to stroke or brain tumours. Six patients with...
Updated staging of LCHADD retinopathy
The authors present their proposal for an updated staging system for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency retinopathy. This is a rare mitochondrial disease due to deficiency of the long chain fatty acid oxidation pathway. Forty patients who were part of...
Stargardt disease in a Turkish cohort
The authors present a study of 27 Turkish patients who were seen in a single centre over a five-year period. All patients had macular optical coherence tomography (OCT), colour fundus photography and 30-2 Humphery visual fields performed, along with clinical...
Treatment of vertical diplopia in the reading position
This paper describes the use of slab-off prisms for the treatment of vertical diplopia in the reading position. The following data were collected: main symptom complaint, visual acuity, refractive error, binocular vision including sensory fusion and stereoacuity, alternating cover test...
PAX6 methylation and myopia
The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...
Myectomy with or without proximal end tucking for inferior oblique overaction
This study aimed to compare the outcomes and impact of inferior oblique muscle myectomy with and without tucking the proximal end of the muscle into Tenons capsule in two surgical groups as a treatment for inferior oblique overaction. Tucking the...
Associations between cerebral vascular malformations and retinal venous malformations
The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...
