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2077 results found

ARN in North Africa

Acute retinal necrosis (ARN) is a rare cause of uveitis. This paper aims to outline the clinical features of 12 patients with ARN in a referral centre in Tunisia, North Africa. A retrospective review of case notes was carried out....

Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma

Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...

Three years of experience with quantiferon-TB Gold Testing in patients with uveitis

Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...

Transcriptomic analysis of ocular tissues

Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...

Acute retinal necrosis: an Indian experience

The authors of this retrospective study aimed to provide clinical outcomes in 62 eyes of 53 patients presenting with acute retinal necrosis. All eyes received intravenous acyclovir (10mg/kg tds) for 7-10 days followed by oral antiviral therapy (valaciclovir 1g tds...

OCT findings after strabismus surgery for macular, choroidal and nerve fibre thickness

This study used OCT to investigate the changes in the central macular thickness, subfoveal choroidal thickness (SFCT) and retinal nerve fibre layer (RNFL) after horizontal rectus surgery for patients with strabismus. This was a retrospective study and patients were grouped...

Impact of initial management on relapse in Vogt–Koyanagi–Harada syndrome

In this retrospective, multi-centre, observational study, the impact of the initial management of Vogt-Koyanagi-Harada syndrome (VKHS) was assessed by reviewing the records of all patients diagnosed with VKHS between January 2001 and December 2020 in two French tertiary centres, with...

Impact of WASH factors on trachoma prevalence

Trachoma is the leading infectious cause of blindness globally. Following a national population-based trachoma survey in Malawi, one round of azithromycin mass drug elimination (MDA) was carried out successfully – that is, the prevalence of trachomatous inflammation, follicular (TF) in...

Hypothesis for poor visual outcomes in myeline oligodendrocyte glycoprotein-related optic neuritis after first attack

The authors present a retrospective case review with the aim of describing the group of patients with myelin-oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) who had poor visual outcomes following their first attack despite rapid treatment. The study was conducted at a...

The approach to trabeculectomy postoperative complications

Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

Positive diagnosis of acute posterior ischaemic optic nerve neuropathy

Posterior ischaemic optic neuropathy is a rare cause of visual loss believed to be due to infarction in the territory of the pial branches of the ophthalmic artery. There is an absence of clinical signs which means the diagnosis is...

Intracameral antibiotics in cataract surgery: current evidence base

Following on from our recent online survey*, the authors examine the use of intracameral cefuroxime as the standard of care in cataract surgery. Cataract extraction with intraocular lens implantation is one of the most frequently performed surgical procedures in the...