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Clinical Applications of Optical Coherence Tomography Angiography

Clinical Applications of Optical Coherence Tomography Angiography provides an informative, up-to-date review of the numerous applications of OCTA in ophthalmology. This book highlights the ways in which this relatively recent non-invasive imaging technique has been an invaluable tool for our...

Periorbital and subconjunctival emphysema - a sign of orbital rim fracture

Background Orbital emphysema is a condition where air is present in orbit or periorbital tissues [1]. It is most commonly caused by trauma leading to orbit fracture, where air from paranasal sinuses is allowed to enter the orbit. The most...

The Princess Alexandra Eye Pavilion (PAEP) Edinburgh 1969-2019

In the early 1960s plans were afoot to create a new Edinburgh Royal Infirmary to replace the existing building which dated from 1870, it having replaced an earlier one dating from 1729. It was originally planned to build on the...

A life outside ophthalmology

Lloyd Paul Aiello. It was an absolute privilege to speak to Lloyd Paul Aiello, Professor of Ophthalmology, Harvard Medical School, and Vice President of Ophthalmology and Director, Beetham Eye Institute, Joslin Diabetes Center, USA. Prof Aiello is a third-generation ophthalmologist,...

ARx - Augmented Reality Headset

In a continuing look at wearable technology, for those with sight impairment, for Aug/Sep we are looking at the recently released ARx. In previous issues we have covered the Envision Glasses and the OrCam MyEye. The ARx is a device...

Ridley Eye Foundation’s Spring camp programme

The Ridley Eye Foundation continues its work in taking surgery to patients in remote communities living above 2000m in Nepal’s Himalayas. This spring, between 28 March – 7 April 2024, we supported surgical camps in Jumla and Mugu, both in...

Methotrexate and mycophenolate mofetil for non-infectious uveitis

This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...

Treatment efficacy of stage 4 ROP

This study aimed to determine the efficacy of combined vitrectomy and anti-VEGF injection for advanced stage 4 ROP with extensive neovascular proliferation (NF). The study included nine infants; six bilateral and three unilateral. Seven were female and the mean gestational...

Management of ocular surface disease

This is a retrospective study of patients with ocular surface disease (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease), active...

Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases

This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...

Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Tocilizumab in Graves’ orbitopathy

This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...