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Glaucoma and capillary perfusion
Elevated IOP is important but not the sole factor responsible for retinal ganglion cell (RGC) death and optic nerve damage in glaucoma. There is increasing evidence that visual loss correlates with macular inner retinal thinning. A total of 148 eyes...
A novel way to diagnose optic neuropathies using Bruch’s membrane opening
Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...
Relationship between intraocular pressure and optic nerve damage in optic nerve drusen
The authors present a retrospective study exploring the relationship between intraocular pressure (IOP) and optic nerve damage in patients with optic nerve drusen. The aim was to evaluate if patients with normal ocular pressure at the time of optic nerve...
Measurement considerations in OCT results with suspected glaucoma
The purpose of this study was to determine retinal nerve fibre (RNFL) thickness parameters and assess the relationship between the cup-to-disc (CD) ratio and RNFL measurements of paediatric patients who had optic nerve appearance suspicious for glaucoma based on enlarged...
Outcomes of chemo versus no therapy for optic pathway glioma in NF1
The aim of this study was to evaluate the visual outcomes of a cohort of children with optic pathway gliomas and neurofibromatosis type 1 (NF1), with comparison of children treated with chemotherapy or not. This was a retrospective study of...
Assessing possibility of deferring lumbar puncture in mild idiopathic intracranial hypertension
This was a retrospective review of patients consecutively presenting with idiopathic intracranial hypertension (IIH) to a tertiary neuro-ophthalmology clinic without a lumbar puncture (LP) over an eight-year period. Inclusion criteria included true optic disc oedema, retinal nerve layer thickness ≤300µm,...
OCTA optic disc measurement differences between glaucoma and pituitary macroadenoma
This prospective case-control study aimed to assess the potential of optical coherence tomography (OCT) and OCT angiography (OCTA) in distinguishing between glaucoma and pituitary macroadenoma based on optic disc appearance. Thirty-one patients (23 with glaucoma, eight with pituitary macroadenoma) were...
Longitudinal findings in children with neurofibromatosis type 1
This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...
IOP reduction and progression of high myopic glaucoma
This retrospective study of 131 eyes with high myopia (refraction >-6.0 dioptres or axial length >26mm), best corrected vision 20/40 or better, open angle and follow-up period of more than five years, were included from Korea. Based on the intraocular...
Difference in anterior ciliary vessels across horizontal and vertical rectus muscles
In order to obtain more information about anterior ciliary vessels (ACVs), the authors compared bilateral ACVs of the lateral and medial recti muscles and intraoperative observations of the difference of AVC preservation between the lateral rectus and other rectus muscles....
The evolving landscape of diabetic retinopathy
This article outlines efforts to modernise clinically meaningful staging systems and endpoints for diabetic retinal disease (DRD). During a workshop involving over 100 international experts, participants emphasised the need for validated structural and functional endpoints based on the retinal neurovascular...
