You searched for "intravitreal"
The role of inflammation in the pathophysiology of DMO
1 February 2016
| Fiona Harris, Spyridon Chalkiadakis, Simon Taylor (Prof)
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EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...
Neovascular AMD: fresh recommendations underline standards of best practice
1 December 2013
| Rod McNeil
The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...
Complications of limbal stay sutures
There is limited literature describing complications at the limbal suture site. The authors describe two cases with postoperative complications due to use of intraoperative limbal stay sutures. Each case had strabismus surgery at other centres but with presentation to the...What effects do repeated Ozurdex implants have in paediatric uveitis?
The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection
3 October 2024
| Sofia Rokerya
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EYE - Vitreo-Retinal
The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...
Vitreoretinal Disease: Diagnosis, Management and Clinical Pearls (second edition)
A comprehensive, well-illustrated and highly informative resource providing excellent descriptions of vitreoretinal diseases, their presentation, diagnosis and management. The 40 chapters are grouped into four sections, namely: the Anatomy and Physiology of the vitreous, retina, choroid and retinal pigment epithelium;...Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
1 October 2016
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Myopic choroidal neovascularisation
1 August 2015
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...
Aqueous humour cytokine levels in PCV and nAMD
1 April 2015
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Effect of cataract surgery on inflammation control and vision in uveitis patients
1 June 2019
| Ivan Yip
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EYE - Cataract, EYE - Refractive
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cataract surgery, phacoemulsification, uveitis, vision impairment
This retrospective longitudinal study from Moorfields, London, UK compared uveitis recurrence rates and vision loss in 309 eyes of uveitis patients post cataract surgery to 300 control uveitis patients. Cataract is a common complication associated with uveitis and leads to...
Risk factors for lens dislocation post cataract surgery
This retrospective cohort study in Korea assessed the risk factors for intraocular lens (IOL) dislocation. They used national data of 2,162,191 patients who had had cataract surgery between 2009 and 2016. They excluded any patient who had an IOL dislocation...Conservative surgical management of optic disc pit maculopathy
5 August 2020
| Annes Ahmeidat
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EYE - Vitreo-Retinal
Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...