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Histopathological changes in rabbit retinitis pigmentosa
The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...
Case reports of neuro-ophthalmological complications of CIPD
The authors present three cases of neuro-ophthalmological complications of chronic inflammatory demyelinating polyradiculoneuropathy (CIPD). CIPD can lead to prominent nerve hypertrophy which can mimic other forms of neuropathy radiologically. In addition, complications can occur which can cause diagnostic difficulties. All...
An interesting presentation of ruptured anterior communicating artery aneurysm with acute monocular vision loss
The authors report an interesting case of a 60-year-old man presenting with acute monocular vision loss accompanied by periorbital pain as an unusual presentation of subarachnoid haemorrhage (SAH) from ruptured anterior communicating artery aneurysm. The patient did not present with...
Choroidal vascularity in NAION
The authors present a cross-sectional, non-interventional study of healthy volunteers and those with non-arteritic anterior ischaemic optic neuropathy (NAION) recruited over a six-month period at a single site. NAION is the most common cause of acute optic neuropathy over the...
Risk of CNV related to angioid streaks in PXE
This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...
Lagophthalmos as a potential complication of COVID-19
Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...Acute management of retrobulbar haemorrhage
The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...The Makassar-Dundee VISION 2020 LINK: a tale of two cities and two trainees
A resident’s view from Makassar My name is Hendra Kusuma, a final year resident (registrar) in the ophthalmology department at Hasanuddin University in Makassar, Indonesia. We have had a VISION 2020 LINK with Dundee (coordinated at the UK end by...
Aetiology of painful ophthalmoplegia
Painful ophthalmoplegia is a clinical syndrome presenting with periorbital / hemi-cranial pain and ipsilateral ocular motor nerve palsies and can occur with numerous different diseases. In this study, the authors aimed to determine the final definite aetiology among patients with...The interpretation and use of ultrasound biomicroscopy (part 1)
Ultrasound Biomicroscopy (UBM) has become increasingly important for the diagnosis of a variety of anterior segment pathologies. Most ophthalmologists are familiar with conventional B-scan ultrasonography techniques, which operate at lower sound frequencies (7.5 to 20MHz). UBM is an ultrasound technique...
