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Conjunctival inflammation in glaucoma patients

Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...

Use of amniotic membrane in second stage Hughes tarsocunjunctival reconstruction

This is a retrospective, non-comparative interventional case series of 30 patients who underwent amniotic membrane transplantation to lower lid margin as part of Hughes lid reconstruction to prevent a hyperaemic, hypertrophic conjunctival margin with excessive discharge. Patients undergoing more than...

Review of the use of amniotic membrane in restrictive strabismus

This literature review was undertaken to investigate the indications, complications and final results of amniotic membrane (AM) transplantation in ocular motility restrictions. The review (of 1103 papers) outlines the healing process plus use of AM. Excluded papers were those of...

Adjunct amniotic membrane during enucleation for retinoblastoma to prevent implant exposure

Amniotic membrane (AM) has potential for treatment of retinoblastoma (RB) patients with contracted sockets after enucleation. The authors present their experience of AM with enucleation for patients with RB after chemotherapy in this retrospective study of 100 eyes of 107...

Oriel celebrates breaking ground milestone

A special breaking ground celebration was held on 11 July to mark the start of construction to build Oriel, a new eyecare, research and education centre in Camden.

The NRC achieves Carbon Neutrality for the second year running

The NRC has successfully achieved carbon neutrality for 2022, alongside a significant reduction in emissions in a number of areas.

DSEK – five year results

This UK based study examined long-term descemet stripping endothelial keratoplasty (DSEK) results, looking at graft survival and endothelial cell losses. Data on 210 grafts were included in analysis. Most frequent indication for DSEK was Fuch’s endothelial dystrophy (81.4%) and 46.3%...

OCT positioning regimen in macular hole surgery

The authors set out to evaluate an OCT-based positioning regimen for macular hole surgery. Patients were advised to maintain prone positioning until the hole was confirmed to be closed based on daily OCTs. Surgery consisted of 23-gauge phacovitrectomy with internal...

Evaluation of keratometry with a novel colour LED corneal topographer

The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...

Microdroplet and splatter contamination during phacoemulsification in COVID-19 era

Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...

Heidelberg Engineering Celebrates Eye2Gene™ AI Breakthrough in Precision Ophthalmology

Heidelberg Engineering proudly announces a significant advance in the use of artificial intelligence for ophthalmic diagnostics, with the publication of the Eye2Gene™ study in Nature Machine Intelligence. Titled “Next-generation phenotyping of inherited retinal diseases from multimodal imaging with Eye2Gene”, the...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...