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Quality of life concerns after uveal melanoma diagnosis

The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Exploring the potential of neurodegenerative disease screening within age-related eye disease research

The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...

RCOphth Cornea Curriculum Course - 23 & 24 October 2025

The Royal College of Ophthalmologists Cornea Curriculum Course - 23 & 24 October 2025

A nightmare on Doctor Street: Three

“Everyone at this party isn’t as young, fit and single as they’re making out. Yep, let’s face it, we’re all falling apart piece by piece. Doesn’t matter if you’re single or in a couple: You. Are. Going. To. Die” In...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Does beauty truly lie in the eye of the beholder?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does beauty truly lie in the eye of the beholder? Scleral whitening, iris colour-changing drops and...

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

What’s trending Feb/Mar 2026

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Darts #AlyPaly It always looks like an electric atmosphere at Alexandra Palace for the World Darts Championship, and the 2025/2026 competition...

Cyanoacrylate nail glue accidentally instilled into the eye instead of eye drops

Three hundred thousand cataract operations take place each year in the UK alone and each patient will receive a four week course of drops in order to cover them for any postoperative inflammation or infection. Accidental instillation of cyanoacrylate glue...

Apr/May 2015 Quiz

History A 60-year-old man presented to the ophthalmologists with painful blurred left vision. Examination revealed a white vascular mass, occupying 60% of the anterior chamber space, arising from the iris. After conservative therapy, no useful vision remained. The eye was...

Spectacle Makers' Charity: Student Bursary Scheme opens for 2024-25 academic year

The Spectacle Makers’ Charity has this week opened applications for student bursaries for the 2024-25 academic year. Since launch, the bursary scheme has helped more than 120 students enrolled on degree and diploma courses in dispensing, orthoptics, optometry, ophthalmic imaging...