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Broadening horizons in ophthalmology: crafting a varied elective experience

The elective period for medical students is a unique opportunity to immerse oneself in a field of interest. For students interested in ophthalmology, this can offer a dedicated experience for what can otherwise be quite limited through undergraduate rotations. Alongside...

Neurofibromatosis with multiple bilateral choroidal nevi and literature review

The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...

Moorfields: Laser Course

Moorfields Education: Laser course for ophthalmic healthcare professionals

Moorfields DALK wet lab

Deep Anterior Lamellar Keratoplasty (DALK) is the most challenging technique of corneal transplantation. Moorfields Eye Hospital performs a high volume of DALK surgeries and is currently the leading centre in corneal transplantation in Europe. The Moorfields DALK wet lab, delivered...

The medical student syndrome

It is often said that “a little learning is a dangerous thing,” but being super savvy can’t put us at the brink of harm, can it? Each year as thousands of students commence their medical degrees, they begin a journey...

Choroidal melanoma – breaking bad news

Case report A 55-year-old Caucasian female presented to her general practitioner with a three-month history of headaches and worsening blurred vision in the left eye. On further close questioning, she reported no eye pain, intermittent floaters and flashes of light...

A mouse model for uveal melanoma

Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...

Melphalon treatment of retinoblastoma

The purpose of this study was to report the authors’ experience with superselective ophthalmic artery infusion of Melphalon (SOAIM) for the treatment of five cases of unilateral sporadic retinoblastoma involving the macula. Standard therapy included a cycle of three infusions...

Reduction of severe visual loss and complications following IAC for RB

This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Prevalence of strabismus in neurofibromatosis type 1

The purpose of this study was to evaluate the prevalence of strabismus in NF1 by comparing children with normal neuroimaging to those with optic pathway glioma. The study included 236 children with NF1, of which 38 were excluded with no...

Diffuse lamellar keratitis

This study group reviewed cytokine- and chemokine-mediated mechanisms of diffuse lamellar keratitis (DLK) after lamellar corneal surgical procedures. DLK can occur early or late (months to decades) after all lamellar corneal surgeries, including laser in situ keratomileusis, small incision lenticule...