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3rd Annual Retinal Imaging Biomarkers & Endpoints Summit

Accelerate Your Ophthalmic Development with Deep Learning Systems & Sophisticated AI Imaging TechnologiesWith state-of-the-art AI-assisted technology making retinal imaging 100 times faster, the rapid advancement of technology in ophthalmology, coupled with the strong unmet need for more drugs for retinal...

A possible biomarker for diabetic retinopathy

Diabetic retinopathy (DR) is the most common form of diabetic eye disease, characterised by exudates, microaneurysms and haemorrhage. Early diagnosis is crucial for preventing visual loss. The risk of developing diabetic retinopathy is known to increase with age as well...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...

Optical coherence tomography in patients exposed to vigabatrin

Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...

Technology in ophthalmology – a promising future and what we need to know about the regulations

Undoubtedly, ophthalmology is one of the greatest sources of inspiration for technological progress in medicine. Thus far, we have seen remarkable advancements in the technology used by ophthalmologists across all subspecialties. From simplifying common procedures, to treating previously incurable conditions,...

Lateral tarsal strip versus Bick’s procedure in correction of eyelid malposition

The authors report a retrospective case series of patients, to evaluate the effectiveness of Lateral Tarsal Strip (LTS) and Bick’s procedure (lateral wedge resection) for all types of involutional lower eyelid malposition, at two centres between January 2012 and 2015....

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

My journey as advanced ophthalmic emergency nurse practitioner

Grace Eni explores her own achievements as an advanced nurse practitioner, emphasising the influential range and significance of this role in ophthalmic care. A pioneering position and job title in the UK and possibly globally, advanced nurse practitioner roles were...

Optimising the ocular surface by managing meibomian gland dysfunction

Meibomian gland dysfunction (MGD) is ubiquitous. Ocular surface inflammation and irritation are prevalent in most ophthalmology clinics: corneal, cataract, glaucoma, oculoplastic, paediatric, vitreo-retinal, medical retina and refractive surgery. These patients also represent roughly one third of those attending for emergency...

Mindfulness and cataract surgery experience in ophthalmology doctors in training

Mindfulness can be described as the state in which one is to be fully present in the moment, which draws parallels with surgery. The origins of mindfulness stem from ancient Buddhist traditions, and its utilisation in recent times in the...