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Advances and developments in medical retina
The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...When science meets art: Creating brilliant sparks
4 February 2025
| Ningli Wang (Prof), Ning Tian, Mayinuer Yusufu
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EYE - Glaucoma
I was honoured to have the privilege of reconnecting with the Tongren Eye Center team in Beijing, China. Digital art in mainstream media has showcased some glorious works and it is humbling to see and hear about some creative new...
Dec/Jan 2017 Quiz
History An 18-month-old boy presented with a slow growing left anterior orbital lump medially. Examination revealed a palpable mass beneath the skin at the inferonasal aspect without any visual impairment. A CT scan (Figure 1) followed by an excisional biopsy...Cancer associated retinopathy
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...
Preoperative RPE alterations in macular holes
1 April 2017
| Saruban Pasu
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EYE - Vitreo-Retinal
This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...
Effect of anti-VEGF treatment on PED morphology
1 June 2015
| Jaya Myneni
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EYE - Vitreo-Retinal
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers
Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...
CD40L activation of human RPE cells
1 August 2018
| Graham Wallace
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...
More sensitive visual acuity test for age-related macular degeneration
1 October 2016
| Roger S Anderson (Prof), Nilpa Shah
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...
Silent keratitis in failed graft
This study examined rates of asymptomatic keratitis in failed full thickness corneal grafts, which were not picked up clinically preoperatively. During a five year period 53 penetrating keratoplasties (PK) were performed for long-standing graft decompensation with stromal opacity and /...
Nanofiber-based hydrogels prevent capsular opacification
1 April 2016
| Graham Wallace
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EYE - Cataract, EYE - Refractive
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Capsule opacification, Cataract surgery, Epithelial–mesenchymal transition, Nanostructures, Prevention
Lens refilling is the replacement of the lens with a silicone polymer in an otherwise intact lens capsule. However, capsular opacification (CO), resulting in reduced visual acuity, is a major complication of these injectable accommodating lenses. Opacification is due to...
