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Ocular complications in retinal vasculitis
1 February 2018
| Efrosini Papagiannuli
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EYE - Vitreo-Retinal
In this retrospective study the authors aimed to characterise the incidence rates of visual loss and ocular complications associated with retinal vasculitis (RV – annual incidence of 1-2/ 100000/ per annum). A secondary objective was to compare the visual outcomes...
Fingolimod: ocular adverse effects
1 October 2017
| Sofia Rokerya
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EYE - Vitreo-Retinal
In this article the authors review the ocular side-effects of Fingolimod which is an oral immunomodulating drug used in the management of relapsing-remitting multiple sclerosis (RRMS). Fingolimod-associated macular oedema (FAME) is the most common ocular side-effect linked to this drug....
Anterior capsular tears complicating phacoemulsification surgery
This is a retrospective, interventional case series, assessing the occurrence of anterior capsular tears in phacoemulsification surgery, its effect on outcomes and further complications. Despite being a well recognised complication of phacoemulsification surgery the authors felt that there is a...Is there an association between dry eye disease and depression and anxiety?
Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...How does cataract surgery affect eyes with wet AMD?
In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...2018 update on intravitreal injections
1 December 2018
| Sofia Rokerya
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EYE - Vitreo-Retinal
In this review article the authors have highlighted the standardised and structured approach to intravitreal injections (IVI) by examining the recent evidence-based literature. IVI is the most commonly performed procedure worldwide with low potential risk of endophthalmitis. IOP spikes are...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
5 August 2020
| Annes Ahmeidat
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EYE - Pathology, EYE - Oncology
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Brachytherapy, Treatment practices, Uveal melanoma
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
The willingness of patients to participate in an eye donation registry for research
1 October 2021
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EYE - Oculoplastic, EYE - Orbit
This paper explores the willingness of ophthalmic patients to donate their eyes post-mortem for research purposes. A total of 300 German patients with a median age of 70 years (range 19-95) completed the standardised questionnaire; 45.3% were female and the...
Sickle cell maculopathy
1 October 2021
| Sofia Rokerya
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EYE - Vitreo-Retinal
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OCT imaging, Sickle cell disease, Sickle cell maculopathy, Visual impairment
This paper reports the result of a prospective study to analyse the prevalence of sickle cell maculopathy (SCM) and its associations with age, sex, genotype, proliferative sickle cell retinopathy (PSR) stage, and the impact on visual acuity (VA). This study...
Cost-effectiveness of orthoptic-delivered screening versus school nurse screening
The authors describe a long-term audit of outcomes and costs associated with referrals from two established neighbouring school-entry vision screening services in the UK over one academic year with one adhering to national UK screening guidelines more closely than the...Patterns of binocular diplopia in giant cell arteritis (GCA)
3 February 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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Diplopia, giant cell arteritis, population-based
Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...