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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

My Top Five: Innovations in the diagnosis of ocular tumours

Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Eye News Book Competition - Your Chance to Win a Copy

Eye News is delighted to be partnering with NIHR Doctoral Fellow, Specialist Registrar in Ophthalmology, and author Sohaib Rufai for an exciting giveaway for new and old readers alike.

Artificial intelligence in eyecare: how do we ensure new technologies truly benefit our patients?

From monitoring patients with heart disease to improving the early diagnosis of cancer, artificial intelligence (AI) using deep learning techniques is already employed in many different healthcare specialties [1]. In the eyecare field, AI technologies have been used to analyse...

How to pass the FRCOphth part 2 oral exam

If you have got this far in terms of your exams, relax. In terms of pass rate, the hardest FRCOphth membership exams are already behind you. The pass mark for the part 2 oral exam is around 75%, and about...

An introduction to research governance

Research is the process of acquiring new generalisable knowledge and should be fully integrated into health care work. There is a growing drive to encourage and further develop evidence-based practice in ophthalmology so that staff and patients benefit from improved...

The Escape Room and gamification of ophthalmology teaching

Recently, there has been an interesting development in medical education and its ‘gamification’. Educators are constantly looking for new ways to engage their students by adding a friendly element of competition, as evidenced by the great success of online education...

Factors associated with inferior oblique transposition surgery and occurrence of anti-elevation syndrome

The purpose of this study was to correlate the frequency of anti-elevation syndrome (AES) with the magnitude of the anterior transposition of the inferior oblique. This was a retrospective study of 312 eyes of 170 patients. Mean age at surgery...

Surgical outcomes after trauma-induced cataract extraction

This study evaluated outcomes in children aged less than eight years with corneal laceration and traumatic cataract who had cataract extraction one to eight weeks after primary corneal wound repair. This was a retrospective study of 47 eyes of 47...

BT for retinal detachment strabismus (2020)

The authors report updated experience on factors influencing botulinum toxin (BT) outcomes for strabismus following retinal detachment surgery. This was a retrospective review of 32 patients with follow-up of 20 months (1-132). Mean age at BT injection was 44 years...

Birdshot retinochoroiditis

Birdshot retinochoroiditis (BRC) is a chronic, sight-threatening uveitis, most commonly affecting caucasian individuals in their fourth to sixth decades [1]. The disease is associated with HLA-29 and is characterised by progressive inflammation at the level of retina and choroid, with...

Amblyopia treatment

This study was conducted to assess practice preferences in the management of amblyopia among paediatric ophthalmologists. A close-ended multiple choice questionnaire consisting of 10 questions was circulated to 113 paediatric ophthalmologists and fellows of which 74 completed the questionnaire. Seventy-six...