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Seminars in Ophthalmology journal cover image

The effects of anti-VEGF therapy for NvAMD on retinal vasculature

4 August 2021 | | EYE - Vitreo-Retinal | aflibercept, foveal avascular zone, neovascular age-related macular degeneration, ranibizumab, retinal vessel density
This retrospective consecutive case series examined 54 eyes of 54 treatment-naïve neovascular age-related macular degeneration (N-AMD) patients. Thirty-three eyes received intravitreal aflibercept injections, and 21 eyes received intravitreal ranibizumab injections with unaffected fellow eyes (54 eyes) as controls. All image...

Internal limiting membrane (ILM) peeling on blood flow in diabetic macula

2 February 2024 | | EYE - Vitreo-Retinal | Diabetes, Epiretinal membrane, Inner limiting membrane, vessel density, vessel length density
This is a retrospective review of notes for diabetic patients with epiretinal membrane (ERM) who underwent surgery by the same surgeon. Nineteen had ERM peeling only, while the remaining 18 had both ERM and internal limiting membrane (ILM) peeling. The...

Conservative management of concomitant strabismus

1 October 2019 | | EYE - General
The aim of management for all patients with strabismus should centre around four goals: to prevent amblyopia, to alleviate symptoms, to restore binocular single vision (BSV) and to improve ocular alignment. The conservative management options available for strabismus include observation,...

Addressing medical risk factors for diabetes and understanding the new systemic treatments

1 February 2014 |
As global diabetes figures continue to rise, the importance of reducing the burden of macrovascular and microvascular complications of diabetes has never been so great. By 2025 it is estimated that five million people in the UK will have diabetes...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | | EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

It’s not all about ARED - Time for a pragmatic approach to nutrition for eye health?

1 April 2016 | | EYE - Cornea
Advances in treatment for retinal diseases involving neovascularisation have undoubtedly changed the future of eye care across the UK for the better, but also created great challenges for service delivery in ophthalmology, particularly within the NHS. Some statistics are starting...

Only fools and doctors

2 April 2025 | | EYE - General
“Alright, this is where our future lies Rodney. Second hand motors. This time next year we’ll be millionaires.” The above is the well-known quote by the happy-go-lucky Del Boy from the famous British sitcom, Only Fools and Horses, forever on...

Radiation retinopathy

5 June 2020 | | EYE - Vitreo-Retinal, EYE - General
The authors review the current treatment options for this condition. Radiation retinopathy (RR) occurs as a complication after exposure to any type of radiation (external beam, plaque brachytherapy and stereotactic radiosurgery) in the orbital or adnexal region. These include nasopharyngeal...

Covid-19

23 March 2020 | | EYE - General
I am writing this on 21 March 2020, and I am pretty confident that by the time you read this that whatever I say will already be hopelessly out of date. Plus, it’s only really what I think, and I...

Simulation in ophthalmology: a pedagogic viewpoint

1 April 2017 | | EYE - Cataract, EYE - Refractive
The advent of simulation technology has enhanced modern medical training. The first utilisation of simulation was in 1929 where Edward Link used this concept to develop a mechanical flight simulator [1]. Industries such as aviation, nuclear power and the military...

It’s Friday, I’m In Love: Pete’s Hidden Curriculum Part 3

3 February 2023 | | EYE - General
“When you’re in love, it’s the most glorious two-and-a-half days of your life.” - Richard Lewis [1]. The good news is that we are over the hump now and past the most depressing day of the year, which is known...

Screening for Sickle Cell Retinopathy (SCR): Why we do wide-field imaging, OCT/OCT-A for SCR – Newcastle upon Tyne Hospitals NHS Foundation Trust

1 June 2022 | | EYE - Vitreo-Retinal, EYE - Imaging
I have been working in ophthalmology for over five years as a photographer and research co-ordinator, and it is fascinating, rewarding, and interesting to learn all about the different diseases associated with the eye. One condition that has been a...