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The Story of Looking: Mark Cousins
Lake, Sweden, as featured in The Story Of Looking. In an interview with Director Mark Cousins about his relationship with sight and storytelling, Peter Cackett discusses Cousins’ recent film, The Story of Looking, and how its production informed, and was...
Carbonic anhydrase II autoantibody specificity in retinopathy
Autoimmune retinopathy (AR) can be divided into three different categories, paraneoplastic retinopathy, including recoverin-associated retinopathy and melanoma-associated retinopathy, non-paraneoplastic autoimmune retinopathy, combined paraneoplastic optic neuropathy and retinopathy (CAR). These conditions are characterised by circulating anti-retinal autoantibodies, possibly due to a...
Corneal thickness in patients with diabetic peripheral neuropathy
This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...Acute uveitis from late migration of soft lens matter 10 years post cataract surgery
A 58-year-old Caucasian male presented to the emergency eye clinic with a two-day history of a painful, red left eye and blurred vision. His past ocular history included uncomplicated left phacoemulsification cataract surgery in 2010 and left retinal detachment repair...
Placement of an eyelid weight as an upper lid spacer for lagophthalmos
Upper lid loading with a weight is a well described procedure for the treatment of lagophthalmos and exposure keratopathy. The authors describe a modification of this procedure whereby the levator aponeurosis is recessed in combination with supratarsal weight implantation. The...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
MicroRNA inhibits corneal neovascularisation
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
Corneal stroma modelling under hypoxic conditions
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
