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1824 results found

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Diclofenac versus Bromfenac after cataract surgery

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used after cataract surgery to reduce inflammation and cystoid macular oedema (CMO). Diclofenac 0.1% is used three to five times daily for 28 days and Bromfenac 0.09% twice daily for 14 days postoperatively. The...

IOL tilt with air tamponade vs. salt solution

In this study the authors made a comparison of significant postoperative tilt of IOL with air tamponade as opposed to balanced salt solution, in the procedure of combined phaco with IOL and vitrectomy. Thirty-four patients were included into the analysis....

Ozurdex in epiretinal membrane surgery

This was a prospective multicentre pilot study, looking at the effect of Ozurdex on visual acuity (VA) and central retinal thickness (CRT) in patients undergoing surgery for epiretinal membrane (ERM). Twelve eyes of 12 patients were included in the study....

Delayed angle closure in pseudophakia and repeated intravitreal therapy

The authors report two cases of acute angle closure many years after uneventful cataract surgery and posterior chamber intraocular lens (IOL) implantation. Both patients had neovascular age-related macular degeneration (AMD) and received regular intravitreal injections (24 and 25 injections in...

Migraine attack: does retinal and peripapillary blood flow change?

This prospective clinical study compared retinal and peripapillary blood flow parameters in migraine patients during an attack with healthy controls using optical coherence tomography angiography (OCTA). OCTAs were performed on 52 eyes from 26 migraine sufferers and 48 eyes from...

Microperimetry measurements in anisometropic amblyopia

The authors aimed to evaluate retinal sensitivity and fixation characteristics in children with anisometropic amblyopia by macular analyser integrity assessment (MAIA) microperimetry and to compare the results between amblyopia and fellow eyes. The study included 39 children; 21 female –...

Changes in drusen and retinal layer volumes prior to CNV development

This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...

What is paracentral acute middle maculopathy?

This is a review article characterising a clinical entity called paracentral acute middle maculopathy (PAMM). The article highlights the fact that retinal capillary plexuses are organised predominantly into three trilaminar capillary layers occupying the area between the nerve fibre layer...

Association of pendular waveform and retinal disorders

The authors aimed to evaluate the relationship between retinal disorders and pendular low amplitude high frequency components (PLAHF) waveform by collecting nystagmus eye movement recordings, electroretinography (ERG) and gene tests. Retinal disorders were diagnosed by clinical phenotype and genotype characteristics....

Complications after cataract surgery in high myopes: a systematic review and meta-analysis

The authors review all the modern literature on complications after phacoemulsification in high myopes with axial lengths (AL) greater than 25.0mm. Twenty-eight studies reporting on 19,586 eyes were included. The corrected distance visual acuity (CDVA) improved from 0.96 ± 0.53...

Aflibercept (AF) for age-related macular degeneration (ARMD): four-year outcomes of a ‘’treat-and-extend’ (T&E) regimen with exit-strategy

This is a retrospective observational study of 82 patients, between 2014 to 2016 from Switzerland of treatment-naive patients with nARMD, treated with AF, with specific T&E protocol without a loading phase and predefined exit criteria and patients were observed three...