You searched for "Ocular"

1824 results found

Effectiveness and Safety of Dexamethasone implants for post surgical macular oedema including Irvine-gass syndrome

This is a retrospective, multicentre, uncontrolled, consecutive case series from Lyon, France between April 20111 to June 2014, with minimum of one year follow-up. The clinical features including the best corrected acuity (BCVA), central subfield macular thickness (CSMT) and intraocular...

Amblyopic choroidal thickness

The authors studied choroidal thickness in 38 paediatric cases (76 eyes) with unilateral amblyopia to evaluate the differences between amblyopic and fellow eyes, and compare them with 19 healthy control subjects (38 eyes). Anisometropic amblyopia was present in 17 cases...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

ILM peeling in primary rhegmatogenous retinal detachment

This author retrospectively analysed the correlation between internal limiting membrane (ILM) peeling and the occurrence of a postoperative epiretinal membrane (ERM) in patients who underwent vitrectomy for rhegmatogenous retinal detachment (RD). There were 135 medical records investigated. Seventy patients underwent...

Cataract surgery in uveitis

This is a multicentre study of eight UK independent sites of patients with uveitis, undergoing cataract surgery between January 2010 and December 2014. A total of 1173 eyes were compared with a control reference group of 95,573 eyes from the...

ABCA1 mediates lipid efflux in the retina

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...

Ametropic amblyopia and stereopsis

This study aimed to evaluate the correlations between ametropic amblyopia (hypermetropic – 110, myopic – 30, and astigmatic – 65) and stereopsis in 205 children – mean age of 5.2 years ±1.8. For near stereopsis, significant results were found for...

Methotrexate and mycophenolate mofetil for non-infectious uveitis

This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...

Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide

X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...

Gender variations in retinopathy

The Tromso Eye Study is a substudy of the Tromso Study; a population based longitudinal study based in Norway. The extensive 5869 participants had no diabetes and were aged between 30-87 years. Retinal images from both eyes were taken using...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

Microperimetry of subretinal drusenoid deposits

Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...