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Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...It’s not all about ARED - Time for a pragmatic approach to nutrition for eye health?
Advances in treatment for retinal diseases involving neovascularisation have undoubtedly changed the future of eye care across the UK for the better, but also created great challenges for service delivery in ophthalmology, particularly within the NHS. Some statistics are starting...Urban Changes and Rural Struggles for Ophthalmology in China
China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...The Worshipful Company of Spectacle Makers rewards early career research
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of its annual bronze medal award competitions for vision research. Both the winning submissions demonstrated models for earlier diagnosis of significant eye disease and have the capacity to...Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
VEGF and axial length (RVU)
The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...
Traumatic macular holes: reconstructive changes in foveal microstructures and visual predictor analysis, following surgical repair
The purpose of this paper was to investigate the reconstructive changes in foveal microstructures postoperatively and analyse the visual predictors in eyes with surgically closed traumatic macular holes (TMHs). This retrospective study analysed the data collected from 71 eyes of...Adaptive optics imaging: resolving single cells in the living eye
The human retina is unique in the central nervous system (CNS) in that it can be directly visualised non-invasively. Technological advances of several imaging modalities, including optical coherence tomography (OCT), multichannel scanning laser ophthalmoscopy (SLO) and fundus photography, have afforded...
Features, treatment and prevention of conjunctival inclusion cysts
Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...A case of late spontaneous subluxation of in-the-bag intraocular implant
An 82-year-old frail lady was referred by her optometrist with a finding of subluxated implant in the right eye. She had uneventful phacoemulcification with in-the-bag intraocular implant 17 years earlier. There is no history of having had pseudoexfoliation (PXF) or...
Detecting apoptosis in retinal cells
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
