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Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

1 December 2014 | | EYE - Vitreo-Retinal
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Beware the disc in myopic patients

1 August 2018 | | EYE - Glaucoma
Glaucoma is a chronic and progressive optic neuropathy characterised by damage of retinal ganglion cells. Evaluation of structural damage of the optic nerve is important in glaucoma diagnosis. The ISNT rule states that the neuroretinal rim width is generally widest...

Culture positivity of needles for IVT injections

1 December 2013 | | EYE - Vitreo-Retinal
Given the worldwide use of intravitreal (IVT) injections, the authors of this paper set out to evaluate the rate of culture positivity of the needles used in routine IVT injections and compare this positivity between 27-gauge and 30-gauge needle tips....
Ocular Oncology and Pathology journal image

Undetected retinoblastoma management following vitrectomy

5 October 2020 | | EYE - Paediatrics, EYE - Strabismus
This retrospective study from a single-centre referral university hospital in Germany analysed data collected between 1991-2019 to comment on management and complications of undetected retinoblastoma eyes following vitrectomy. The 10 patients included had a mean age of 36.1 months (range...
Eye journal cover image.

Current practice and patient selection for ISBCS in the UK

7 December 2020 | | EYE - Cataract, EYE - Refractive
This study investigated patient and operative characteristics for immediate sequential bilateral cataract surgery (ISBCS) and delayed bilateral cataract surgery (DSCS). The annual NHS spend on cataract surgery is £500 million, a figure expected to rise by 50% in the next...

Paraproteinaemia: a patient with atypical corneal findings

1 December 2013 | | EYE - Cornea, EYE - General
A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa [1]. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström’s macroglobulinemia. Multiple...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Understanding amniotic membrane grafts

1 June 2019 | | EYE - Cornea, EYE - General
Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Trainee personality types

5 February 2020 | | EYE - General
Over the past two years I have attended quite a number of medical educational seminars and ‘workshops’ and have been a bit shocked at how out of kilter with reality the world of education seems to be now. It seems...

A comparison of light sources in retinal imaging

1 October 2021 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
Before starting to talk about the light sources present in retinal imaging, it is necessary to start from the base: the light. Light is an electromagnetic wave whose smallest part is the photon (or quantum of light). A high frequency...

The David J Apple International Laboratory for Ocular Pathology – a legacy of pioneering IOL research

1 October 2016 | | EYE - Cataract, EYE - Refractive
David Apple and Gerd Auffarth. The Apple Lab at the David J Apple Center for Vision Research in Heidelberg is a thriving international laboratory for research into intraocular devices. The lab continues the work of David J Apple, a world-renowned...

Blinking blepharitis has a lot to answer for…

1 October 2015 | | EYE - Cornea
Never ignore the small things’…someone once said. There is no doubt blepharitis is one of the most common eye conditions encountered daily, but with the typical pressures of a busy outpatient department, the management of more obvious, sight-threatening conditions necessarily...