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The fragile p-value

5 October 2020 | | EYE - General
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Watch your back: Ergonomics and Ophthalmology

2 August 2022 | | EYE - General
Aadil Hussain discusses an ophthalmologist’s risk of musculoskeletal injury and highlights the importance of ergonomics education, to ensure a pain-free career. Chronic and disabling musculoskeletal injury has been identified in the field of ophthalmology with increasing prevalence. The ophthalmologist is...

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

1 December 2016 | | EYE - Vitreo-Retinal
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

Introduction of the Mydriasert insert at the Manchester Royal Eye Hospital

1 August 2018 | | EYE - Cornea, EYE - General
The authors report on a study to examine the effects of the Mydriasert insert on time, effects, patient comfort and tolerability at Manchester Royal Eye Hospital. Mydriasert is an insoluble ophthalmic insert indicated for mydriasis prior to ophthalmic surgery, which...

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

1 April 2019 | | EYE - Cornea, EYE - General
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...

Sustainability in eyecare: Intraocular gases and the climate emergency

4 August 2021 | | EYE - Vitreo-Retinal, EYE - General
In 2020 the NHS became the first national health system to commit to delivering ‘net zero’ carbon emissions by 2040. The author investigates how the impact of ophthalmic surgery can be reduced. Medical gases have been used in ophthalmic surgery...

100 years of insulin

3 October 2022
*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Issues with standard practice: Luer lock syringes in cataract surgery

4 December 2025 | | EYE - Cataract
For a few years, we have worked together with the practice variance surveys to tease out differences in the way we work and to discuss issues that arise. I hope that we have learnt some lessons and reflected on what...

The eye without tears

1 June 2016 | | EYE - General
The Art is long and Life is short. So goes the dispiriting tag in Latin and flung from day one and at regular intervals thereafter at idle medical students who, inevitably brainwashed, come by graduation to believe that the only...

The Gambia-Swansea VISION 2020 LINK: building eye care services and international friendships

1 June 2014 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History The VISION 2020 LINK between the Sheikh Zayed Regional Eye Care Centre (SZRECC), Banjul, The Gambia and the Ophthalmology Department, Singleton Hospital, Swansea started in 2008 under the guidance of the VISION 2020 LINKS Programme at the International Centre...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

A closer look at the new wave of glaucoma surgery – radical or old school?

1 October 2016 | | EYE - Glaucoma
Glaucoma is a challenging condition to treat because the exact pathophysiology remains unclear and the only readily modifiable factor is the intraocular pressure (IOP). Additionally, most glaucoma patients are completely asymptomatic, yet are often subjected to lifelong medical therapy. The...