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Sexually transmitted conjunctivitis – the REALLY sticky eye
Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis
Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...Feb/Mar 2014 Quiz 2
1 February 2014
| Imran Ashfaq, Rajen Gupta
|
EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Oculoplastic, EYE - Neuro-ophthalmology, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 65-year-old lady presented with a ten year history of nonspecific visual disturbance and mild symptoms of dry eyes. Questioning revealed progressive nyctalopia. Previous medical history of note included Crohn’s disease requiring two bowel resections including small intestine. Figure...
Gene therapy: perspectives from young adults with Leber’s congenital amaurosis
5 June 2023
| Ivan Yip
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EYE - Vitreo-Retinal
The authors present their telephone survey data of 10 patients with a mean age of 24.4 years regarding their opinion on gene therapy for their Leber’s congenital amaurosis. Patients were recruited at the Hospital for Sick Children, Toronto. Of the...
Comprehensive review of inherited retinal diseases
3 June 2024
| Zhihang Cheng
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EYE - Vitreo-Retinal
The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...
Cavernous sinus syndrome
Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...Acute dellen formation post trauma
1 January 2016
| Lucia Derriman, Andrew Pearson
|
EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Corneal dellen are saucer-like thinnings, usually of the peripheral cornea [1]. Dellen formation is thought to be related to localised tear film instability [2], specifically the absence of the mucin component of the tear film. Without the mucin layer, dry...
Conjunctival lesions in paediatric patients
This article documents the conjunctival lesions in paediatric patients from one unit from 2011–22 inclusive in the UK. There was a total of 85 cases with a mean age presentation of seven years old. Most common lesions were naevi (40%),...Endoscopic assisted probing for congenital nasolacrimal duct obstruction
In this retrospective study authors compare the success rate of nasal endoscopic-assisted probing between younger (three years and below) and older (three years and above) children with membranous nasolacrimal duct obstruction and its correlation with the thickness of the membrane...Outcomes from evisceration with primary implant in 1800 patients
This is a retrospective analysis of 1800 patients who had evisceration with orbital implant between 2013-2019. As the largest published series on this topic, the authors are able to give relatable real-world data on complications following surgery. They use a...Long-term effect of gene therapy on Leber’s congenital amaurosis
1 October 2015
| Jonathan CP Roos
|
EYE - Vitreo-Retinal
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...