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Non-organic visual loss
Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...The role of inflammation in the pathophysiology of DMO
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...An anterior segment lump: a diagnostic and treatment challenge
Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...Brain tumours in adults: the essentials for an ophthalmologist
The author provides a review of the common intracranial tumours in adults (other than pituitaries) which may present to an ophthalmologist. Primary malignant brain tumours comprise 3% of adult cancers but with an ageing population such tumours are becoming more...
Microbial keratitis in corneal grafts
The authors report a retrospective case series of 59 episodes of microbial keratitis identified in 41 eyes of 41 patients (39 penetrating keratoplasty (PKPs) and two deep anterior lamellar keratoplasty (DALKs)), from a total of 759 consecutive corneal grafts identified...The eye without tears
The Art is long and Life is short. So goes the dispiriting tag in Latin and flung from day one and at regular intervals thereafter at idle medical students who, inevitably brainwashed, come by graduation to believe that the only...
Accuracy of clinician vs. radiologic interpretation of the imaging of orbital lesions
This is a retrospective study of 242 patients who underwent surgical orbitomy at University of California Davis Health between 1 January 2000 and 20 May 2019. The preoperative imaging with radiologist’s interpretation, clinical assessment with clinician’s interpretation of imaging, and...
Distribution, progression, and outcomes of inflammatory chorioretinal lesions
This study investigated the distribution and progression of multifocal choroiditis (MFC) inflammatory lesions in 25 eyes of 20 patients and their correlations with clinical outcomes at 24 months. The distribution of choroiditis inflammatory lesions were evaluated semi-automatically using a dedicated...Clinical relevance of the anatomic classification of neovascular age-related macular degeneration
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...
Visual prognosis in Irish Leber’s hereditary optic neuropathy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...
ILM peeling in proliferative diabetic retinopathy: a meta-analysis
This meta-analysis highlights the efficacy of internal limiting membrane (ILM) peeling on treating posterior segment complications other than macular oedema in patients with proliferative diabetic retinopathy (PDR) treated with vitrectomy. PubMed, EMBASE and Cochrane Library were searched for databases. Eleven...
