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Conference Report: UCL Institute of Ophthalmology Summer School 2025
The UCL Institute of Ophthalmology Summer School 2025 was held in collaboration with Moorfields Eye Hospital run by Gordon Hay and Tara Bader. This was a comprehensive five-day course attended by medical students and resident doctors from around the world....The refractive index in the eye lens – implications for clinical practice and optical design
The eye may appear to be a comparatively simple organ and yet its optical system is complex and continues to be a source of investigation and research. The major optical elements are considered to be the cornea and the lens...Conservative management of concomitant strabismus
The aim of management for all patients with strabismus should centre around four goals: to prevent amblyopia, to alleviate symptoms, to restore binocular single vision (BSV) and to improve ocular alignment. The conservative management options available for strabismus include observation,...Cybersight: Using OCT as an Approach to Diagnose Glaucomatous and Other Optic Neuropathies
Clinically, the difference between glaucomatous and simple optic atrophy of other origins is not always clear. OCT with the ability to image and measure inner retinal layers in the macula and peripapillary area, with the measurement of rim atrophy, is...
Use of RAPDx device with optic nerve disease
The authors have previously reported on use of the RAPDx device for evaluating relative afferent pupillary defects (RAPD). RAPDx objectively determines the magnitude of RAPD by presenting light stimuli alternately to pairs of eyes with laterality. The parameters of amplitude...
Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure
The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...
An interesting presentation of ruptured anterior communicating artery aneurysm with acute monocular vision loss
The authors report an interesting case of a 60-year-old man presenting with acute monocular vision loss accompanied by periorbital pain as an unusual presentation of subarachnoid haemorrhage (SAH) from ruptured anterior communicating artery aneurysm. The patient did not present with...
Prevalence of strabismus in neurofibromatosis type 1
The purpose of this study was to evaluate the prevalence of strabismus in NF1 by comparing children with normal neuroimaging to those with optic pathway glioma. The study included 236 children with NF1, of which 38 were excluded with no...
A novel presentation of optic disc oedema with syphilis
Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....
Transient visual loss caused by crowded optic discs
The author presents four cases of transient visual loss (TVL) in young females (age range at presentation 14-22 years) with crowded optic discs. Patient demographics, investigations, medical and social histories are provided for all patients. A review of evidence for...
New prognostic model for multiple sclerosis after optic neuritis presentation
The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...
