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1833 results found

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...

Identification and diagnosis of thalamic haemorrhage

This paper presents a case of thalamic haemorrhage and discusses clinical findings, providing valuable insight into signs clinicians need to look for. The case presented is of a 76-year-old female who developed left hemiplegia and hemi anaesthesia. Ocular motility testing...

Prognosticating ocular adnexal lymphoma

The authors retrospectively analyse 160 patients with primary ocular adnexal lymphoma to determine the accuracy of prognosis based on the Ann Arbor classification and how this compares to the accuracy of prognosis based on retrospectively applying the newer Tumor, Node,...

Clinical and neuro-ophthalmologic predictors of visual outcome in idiopathic intracranial hypertension

This prospective study of 40 patients aims to assess visual morbidity in patients with idiopathic intracranial hypertension (IIH). Final visual outcome of patients was compared with clinical and neuro-ophthalmic parameters such as visual acuity, visual field, contrast sensitivity, retinal nerve...

Reduction of severe visual loss and complications following IAC for RB

This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...

Selection of visual field test for detection of pituitary disease

This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...

Visual impairment in patients with glaucoma

This retrospective observational study assessed the prevalence of end-of-life visual impairment in patients with glaucoma. A total of 122 deceased patients followed for glaucoma were included and data was collected from patient notes. Sixty-one patients had open-angle glaucoma and 61...

Glasses or not?

In this excellent review article, the authors discuss how some hyperopes avoid strabismus but also ask why the youngest infants escape strabismus and older patients go on to decompensate. The review considers a number of related aspects and their inter-relations...

Nanoparticle administration of latanoprost

Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...

Prediction of visual outcome in IIH

In this prospective study, visual outcome of 40 patients with idiopathic intracranial hypertension (IIH) was compared with clinical and neuro-ophthalmic parameters. The purpose of this was to determine any correlation to try and predict visual outcome for IIH patients. Parameters...

Lens surgery in patients with lens subluxation misdiagnosed as primary angle-closure glaucoma

Lens subluxation can be caused by many conditions including Marfan syndrome and other hereditary conditions, and blunt trauma. Lens displacement can cause pupillary block and angle closure. This is commonly misdiagnosed as primary angle closure glaucoma (PACG), which can lead...

Investigation of blood platelet parameters in anterior ischaemic optic neuropathy

The aim of this clinical retrospective comparative study was to assess the possible relationship between arteritic anterior ischaemic optic neuropathy (AAION) and non-arteritic anterior ischaemic optic neuropathy (NAION) with blood platelet parameters and neutrophil-to-lymphocyte ratio (NLR). The medical records of...