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Retinal changes in Leber hereditary optic neuropathy
The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...
Use of RAPDx device with optic nerve disease
The authors have previously reported on use of the RAPDx device for evaluating relative afferent pupillary defects (RAPD). RAPDx objectively determines the magnitude of RAPD by presenting light stimuli alternately to pairs of eyes with laterality. The parameters of amplitude...
Aflibercept, bevacizumab or ranibizumab for DMO
This is a two-year randomised clinical trial of 660 patients with visual acuity impairment from diabetic macular oedema (DMO) who were randomised to monthly injections of 2.0mg aflibercept, 1.25 mg bevacizumab or 0.3mg ranibizumab. Focal or grid laser was performed...
Iranian strabismus prevalence
This study aimed to evaluate the prevalence of heterotropia and heterophoria in Iran. This was a cross-section study undertaken in 2013 with the target population of grade 1 (seven-year-old) children. Seven cities across different geographical locations were included with multistage...
Nanofiber-based hydrogels prevent capsular opacification
Lens refilling is the replacement of the lens with a silicone polymer in an otherwise intact lens capsule. However, capsular opacification (CO), resulting in reduced visual acuity, is a major complication of these injectable accommodating lenses. Opacification is due to...
Aflibercept for the treatment of neovascular glaucoma
The aim of this study was to investigate initial results regarding the treatment of neovascular glaucoma (NVG) with intravitreal aflibercept. NVG is classified into stages 0-3. In stages 1 and 2, abnormal vessel proliferation is seen with or without elevated...
Syndromic V-pattern management
The authors document their experience in the management of four cases of Crouzon syndrome and review the anatomical extraocular muscle anomalies noted during surgery. Horizontal strabismus surgery varied in each of the four cases according to individual extraocular muscle abnormalities...
Surgical complications of ReLEx
Femtosecond laser refractive lenticule extraction (ReLEx) is a novel procedure for treatment of myopia and myopic astigmatism, which eliminates the use of microkeratome and excimer laser. Currently there are two techniques: FLEx – femtosecond lenticule extraction (similar to conventional LASIK)...
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Systemic anti-inflammatory versus fluocinolone acetonide intraocular implant
In the Multicenter Uveitis Steroid Treatment (MUST) trial, 255 patients with intermediate uveitis, posterior uveitis or panuveitis were randomised to either fluocinolone acetonide intraocular implant or systemic corticosteroid therapy which was supplemented with immunosuppression if required. Patients were followed up...
Ozurdex wound leakage
This letter to the editor describes two cases of wound leakage after Ozurdex injection. The first case is a man who had four previous injections for an underlying diagnosis of chronic serpiginous choroiditis, who was also on a course of...
