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Neurofibromatosis with multiple bilateral choroidal nevi and literature review

14 November 2024 | | EYE - Imaging, EYE - Oncology, EYE - Vitreo-Retinal
The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...

Papilloedema: an update

1 June 2016 | | EYE - Neuro-ophthalmology
Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...

Retinoblastoma management update (part 1): clinical features, diagnosis and genetics

1 January 2017 | | EYE - Oncology
The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...

IgG4 related orbital disease

1 June 2018 | | EYE - Oculoplastic, EYE - Orbit
This retrospective study was done to determine the prevalence of IgG4 related orbital disease (IgG4ROD) in patients who previously had biopsies for suspected idiopathic orbital inflammatory disease (IOID) and / or orbital lymphoproliferative disease (OLD). The charts and slides of...

A standardised strategy for uveitis etiological diagnosis

1 August 2017 | | EYE - Vitreo-Retinal
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...

Shedding light on Wolfram syndrome: The unveiling of a delayed diagnosis

12 August 2025 | | EYE - Neuro-ophthalmology
Wolfram syndrome 1 (WS1) was first described by Wolfram and Wagener in 1938 and it’s a rare neurodegenerative, progressive disorder, also known as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) [1]. We present an atypical case of WS...

SILMO 2019: Anything goes, but sustainability grows

29 October 2019
Trying to spot the trends at this year’s SILMO in Paris, one of the largest optical fairs in the world, was a tough ask. Thin metals, especially in rose gold, abounded, but that’s now; tomorrow remained elusive.

Everyone has a plan, until their hand goes numb…

4 December 2025 | | EYE - Cataract
Cataract surgery is the most frequently performed surgical procedure in the UK [1]. With financially strained NHS trusts and the rise of independent sector cataract providers, the drive from initiatives like Get It Right First Time (GIRFT) and market pressures...

Two cases of acute syphilitic posterior placoid chorioretinitis

4 December 2025 | | EYE - Imaging, EYE - Vitreo-Retinal
Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...

Sexually transmitted conjunctivitis – the REALLY sticky eye

5 October 2020 | | EYE - Cornea, EYE - General
Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...

Cytomegalovirus retinitis post intravitreal triamcinolone in an immunocompetent patient with juvenile glaucoma

1 December 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Figure 1: Fundus photograph shows active CMV retinitis four weeks after IVTA in the right eye. Figure 2: Fundus photograph of the left eye with no CMV retinitis; atrophic disc as a result of juvenile glaucoma. Case report A 29-year-old...

An unusual case of acute retinal necrosis

1 August 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Case report A 40-year-old Caucasian male presented with a four-day history of redness and progressive painless reduction of vision in the left eye. His visual acuities were 6/4 in the right and 6/36 in the left. The left eye showed...