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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Introduction to Visual Optics: A Light Approach

In Introduction to Visual Optics: A Light Approach, Samantha Strong brings fresh life to a traditionally dense topic, making optics accessible, engaging, and even enjoyable. With a conversational tone and clear organisation, Strong guides readers through complex concepts in a...

The symbolism of eyes in Halloween traditions and popular culture

Halloween is a festival steeped in symbolism. Pumpkins, skeletons, ghosts and witches dominate the seasonal iconography, each representing broader cultural anxieties about death, darkness and the supernatural. Among these motifs, the eye, often depicted as glowing, disembodied or grotesquely exaggerated,...

Factors associated with inferior oblique transposition surgery and occurrence of anti-elevation syndrome

The purpose of this study was to correlate the frequency of anti-elevation syndrome (AES) with the magnitude of the anterior transposition of the inferior oblique. This was a retrospective study of 312 eyes of 170 patients. Mean age at surgery...

Delayed improvement in Muller’s muscle ptosis surgery

This is a retrospective review of patients undergoing ptosis surgery. The authors had noticed anecdotally that although a posterior approach Muller’s muscle and conjunctival resection (MMCR) appeared to achieve similar results to an anterior approach levator resection (ALR) in the...

Survey reveals poor public awareness of dry eye disease

A new survey has revealed how few people are aware of Dry Eye Disease, a debilitating and painful eye condition which affects one in four people in the UK.

Cambridge Ophthalmological Symposium 2024: Evolution and the Eye

by Anushka Irodi, Y5 Medical Student, University of Cambridge, UK. The 52nd Cambridge Ophthalmological Symposium, a renowned two-day national meeting, took place on September 5th and 6th, 2024 at St John’s College, Cambridge, UK. It brought together international leading minds...

Acute dellen formation post trauma

Corneal dellen are saucer-like thinnings, usually of the peripheral cornea [1]. Dellen formation is thought to be related to localised tear film instability [2], specifically the absence of the mucin component of the tear film. Without the mucin layer, dry...

Newer generation IOL platforms designed for high-quality visual performance after cataract surgery

Expanding intraocular lens (IOL) capabilities provide broadening options, ranging from next-generation monofocal IOLs for basic cataract surgery, to specialised premium IOLs for lens-based presbyopia correction and astigmatism correction at the time of cataract surgery. Rod McNeil considers several newer alternative...

Current concepts of the uveitis-glaucoma-hyphaema (UGH) syndrome

The authors discuss pathophysiology, aetiology and current management strategies of UGH syndrome. The clinical features of UGH are different than initial descriptions. UGH today is most often associated with posterior chamber IOLs that are not placed within the capsular bag...

Predicting ischemic lesion location using perimetry

The authors present a retrospective records review, using the search terms homonymous hemianopia, visual field loss and MRI. Only posterior circulation artery territory ischemic strokes were included. Demographics, stroke details and initial and follow-up with 24-2 SITA Standard perimetry results...

Surgeons can lead the way in transforming global health

Surgeons must provide leadership in transforming healthcare across the Global South – by integrating surgery into the global health agenda and advocating for simple and cost-effective surgical procedures that support overall health system strengthening.