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This study evaluated the effects of botulinum-toxin (BT) on management of Duane’s retraction syndrome along with how BT can be used diagnostically to help with patient expectations and decide management. Functional and psychosocial impact of BT effect was evaluated in 25 patients; 10 males and 15 females aged mean 21.34 ±3.7 years. The right eye was involved for eight patients and the left for 17. Esotropia was present in 10 patients, exotropia in seven and orthotropia in eight. The preoperative angle was mean 26.32 V15.71PD. Mean AS20 quality of life score was 67.96 ±7.53. There were no major complications – three had mild ptosis. A significant improvement in quality of life was noted after BT. The authors conclude BT was useful as a diagnostic tool but not as a definitive management.

Duane’s retraction syndrome: the role of botulinum toxin A injection in adults and its impact on quality of life in an Indian population.
Anand K, Hariani A, Kumar P, et al.
JOURNAL OF PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2023;60:46-51.
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CONTRIBUTOR
Fiona Rowe (Prof)

Institute of Population Health, University of Liverpool, UK.

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