Journal Reviews

Allografts in limbal stem cell deficiency

1 August 2015 | | EYE - Cornea, EYE - General | Cadaveric keratolimbal allograft, limbal stem cell deficiency, limbal stem cell transplantation, live related allograft

This prospective comparative study compared outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency secondary to ocular burns. Twenty patients were randomly allocated into each group. The Lr-CLAL group had a significant...

Inhibiting high-risk corneal allografts

1 October 2014 | | EYE - Cornea, EYE - General | T regulatory cells, Tim-1, high-risk corneal allograft rejection, mice

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...