Journal Reviews

MicroRNAs in cataract

1 August 2016 | | Cataract and Refractive | Age-related cataract, Lens epithelial cells, Lgr4, MicroRNA let-7b, Ultraviolet irradiation

In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...