Post hoc analysis of the CANTREAT randomised trial
1 December 2023
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Age-related macular degeneration, Randomized clinical trial, Ranibizumab, Treat-and-extend
CANTREAT, a Canadian multicentre two-year randomised trial compares treat and extend treatment (T&E) relative to the monthly administration of Ranibizumab in nAMD. Two-hundred and eighty-five treatment-naïve patients with nAMD were randomised to receive either a once-monthly dosing or T&E regimen...
OCTA in geographic atrophy
4 August 2021
| Sofia Rokerya
|
EYE - Vitreo-Retinal
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Age-related macular degeneration, Angiography, Choriocapillaris, Choroid, Optical coherence tomography
In this article the authors aim to give an overview of the current literature concerning the application of OCT-A in geographic atrophy (GA). GA is a disease characterised by loss of outer retinal layers including photoreceptors, degeneration of the retinal...
Characteristics of Charles Bonnet syndrome in patients with neovascular AMD
7 April 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Age-related macular degeneration, Charles Bonnet syndrome, Low vision, Negative outcome, Visual hallucinations
This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...
Changes in drusen and retinal layer volumes prior to CNV development
7 April 2021
| Ed Rule
|
EYE - Vitreo-Retinal
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Age-related macular degeneration, Choroidal neovascularisation type, Drusen load, Imaging biomarkers, Retinal layer volumes
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
