Journal Reviews
Detecting apoptosis in retinal cells
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
Occult central retinal artery occlusion
Central retinal artery occlusion (CRAO) is a sight-threatening condition resulting from occlusion of the central retinal artery and hypoperfusion of the inner retina. Early on, fundal examination may be normal. The authors present a retrospective case series of 11 patients...
Inflammation and microvascular changes in diabetic retinopathy
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
Incidence, microbiological profile and in vitro antimicrobial susceptibility of IK
This is a retrospective single centre study of all patients (with corneal scraping) including their demographic factors, microbiological profiles, and in vitro antibiotic susceptibility of infectious keratitis (IK), studied between 2007 and 2019. The incidence of IK was 34.7/100,000 people...
Effect of long-term RGP-CL wear on keratoconus progression
This is a retrospective study between April and December 2017, of 22 rigid gas-permeable contact lens (RGP-CL) patients (31 eyes) and 15 non-CL patients (20 eyes) who fulfilled the criteria of: 1) >3 years follow-up and 2) Scheimpflug-based corneal imaging...
Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus
This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...
Intraocular pressure changes following TOHM washout
This retrospective study between 2008 and 2019 of 110 eyes with primary open angle glaucoma (POAG), 33 eyes with ocular hypertension (OHT) and 43 eyes with uveitic glaucoma (UG) evaluated the changes in intraocular pressure (IOP) following topical ocular hypotensive...
A survey of neuro-ophthalmologists on use of corticosteroids in giant cell arteritis
While corticosteroids are the mainstay of treatment in giant cell arteritis (GCA), the type, dose, route and duration of treatment remains controversial. The authors surveyed 180 neuro-ophthalmologists on their use of this treatment via email in a two-month period. Results...
A retrospective medical notes review in patients with poor vision due to NAION
Very severe visual loss (hand movements or less) is typical of arteritic anterior ischaemic optic neuropathy (AION) and relatively rare in non-arteritic AION (NAION). This study aimed to report the frequency of very poor visual acuity (VA) in NAION. The...
Long-standing flattening effects on the globe following spaceflight
Posterior globe flattening has been well-documented in astronauts both during and after long-duration spaceflight (LDSF). This globe flattening is thought to be due to the disc centred anterior forces created by elevated volume and / or pressure within the optic...
A case presentation of morning glory disc anomaly and peripapillary staphyloma
The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...
Differences between ages and onset in functional network changes associated with reading Braille
Visual impairment affects learning ability, speed and accuracy required for reading, writing and learning memory in terms of educational performance. Braille training requires decoding of simple dots into meaningful words and sentences. The objectives of this study were to evaluate...
