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Journal Reviews

Bromfenac versus betamethasone in diabetic macular oedema

31 October 2023 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal | Diabetic macular edema, betamethasone, bromfenac, central subfield thickness, intraocular pressure

This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...

The effects of ab-interno XEN gel implantation on postural IOP elevations

4 August 2021 | Su Young | EYE - Glaucoma | Xen gel implant, glaucoma, intraocular pressure, posture, rebound tonometry

The study involved 18 patients with XEN gel implants, 30 patients who had trabeculectomy, and 30 medically managed glaucoma patients. All patients in XEN gel implant and trabeculectomy groups had at least 11 months of follow-up following successful surgery resulting...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

4 August 2021 | Su Young | EYE - Glaucoma | Open-angle glaucoma, brimonidine/timolol fixed combination, intraocular pressure, normal-tension glaucoma, preservative-free

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...

BJO journal cover image

Visual and refractive outcomes and complications in FLACS versus CPS cataract surgery

7 April 2021 | Jonathan Chan | EYE - Cataract, EYE - Refractive | clinical trial, intraocular pressure, lens and zonules, vision

This is a randomised, controlled study of 110 paired eyes from 55 patients that were randomised into either femtosecond laser-assisted cataract surgery (FLACS) or conventional phacoemulsification cataract surgery (CPS) groups. Visual, refractive outcomes, intraocular pressure (IOP) and complications were compared...

Neuro-Ophthalmology journal cover image

Relationship between intraocular pressure and optic nerve damage in optic nerve drusen

7 April 2021 | Claire Howard | EYE - Neuro-ophthalmology | Optic nerve head drusen, intraocular pressure, retinal nerve fibre layer, visual field

The authors present a retrospective study exploring the relationship between intraocular pressure (IOP) and optic nerve damage in patients with optic nerve drusen. The aim was to evaluate if patients with normal ocular pressure at the time of optic nerve...

Lens surgery in patients with lens subluxation misdiagnosed as primary angle-closure glaucoma

1 August 2019 | Kurt Spiteri Cornish | EYE - Glaucoma | Angle-closure glaucoma, intraocular pressure control, lens subluxation, lens surgery, misdiagnosis

Lens subluxation can be caused by many conditions including Marfan syndrome and other hereditary conditions, and blunt trauma. Lens displacement can cause pupillary block and angle closure. This is commonly misdiagnosed as primary angle closure glaucoma (PACG), which can lead...

Glaucoma and capillary perfusion

1 August 2019 | Kurt Spiteri Cornish | EYE - Glaucoma | Glaucoma, OCTA, field of vision, intraocular pressure, macula, optic nerve

Elevated IOP is important but not the sole factor responsible for retinal ganglion cell (RGC) death and optic nerve damage in glaucoma. There is increasing evidence that visual loss correlates with macular inner retinal thinning. A total of 148 eyes...

Short-term effects of intravitreal bevacizumab on the cornea

1 December 2014 | Khadijah Basheer | EYE - Cornea, EYE - General | anterior chamber depth, bevacizumab, central corneal thickness, intraocular pressure, iridocorneal angle, simulated keratometry

Bevacizumab has been extensively used to treat macula oedema and neovascularisation of the retina and it has also been useful in the management of corneal neovascular diseases. This prospective study aimed to provide more information on the effect bevacizumab may...

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