Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?
This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...
Penetrating keratoplasties in infants
This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...
Data update for leading causes of CVI in England and Wales
In this article the authors present an epidemiological update, based on certifiable visual impairment (CVI) registration for figures for sight impairment (SI) in England and Wales from the last report of 2007-2008 to the current data for April 2012 to...
Mast cells in Graves’ ophthalmopathy
1 August 2016
| Bheemanagouda Patil
|
EYE - General
Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...
Acanthamoeba ability to adhere to different contact lenses
This study tested ability of Acanthamoeba lugdunensis trophozoites to adhere to silicon hydrogel contact lenses (SHCL) and how this is influenced by different multipurpose contact lens solutions (MPS). Three generations of SHCL were tested: first generation – Air Optix, second...
Dry eyes after photorefractive keratoplasty
This study examined changes in tear break up time (TBUT), Schirmer test, tear osmolarity and dry eye questionnaire (OSDI) score from prior to photorefractive keratoplasty (PRK), to two months and four months postoperatively. Fifty eyes of 25 patients were examined....
Treatment of Sjogren’s Syndrome dry eye in mouse model
1 April 2016
| Graham Wallace
|
EYE - Cornea, EYE - General
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Autoimmune, Chronic, Conjunctiva, Inflammation, Ocular surface, Sjögren's syndrome
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
Central corneal and epithelial thickness measured by Fourier domain OCT
This study examined intraobserver and interobserver reproducibility of corneal thickness (CT) and epithelial thickness (ET) measurement of Fourier domain OCT (RTVue) in 23 healthy volunteers. RTVue is capable of producing 26,000 A scans per second with depth resolution of 5µm....
Corneal tattooing as treatment for bullous keratopathy
This retrospective study looked at differences in epithelial smoothing in patients with bullous keratopathy (BK) undergoing either corneal tattooing or anterior stromal puncture (ASP). Both procedures were carried out for symptomatic relief in eyes with poor visual potential. Chinese ink...
Resveratrol protects against steroid induced intraocular pressure
1 April 2016
| Graham Wallace
|
EYE - General
|
Glaucoma, Intraocular pressure, Resveratrol, Retina, Steroid-induced, Trabecular meshwork
Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...
DALK as an early therapeutic option for Acanthamoeba keratitis
Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...
Familial Mediterranean Fever and keratoconus
This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...
