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Journal Reviews

Is myopia protective against progression of diabetic retinopathy?

2 December 2019 | Tasmin Berman | EYE - Vitreo-Retinal

This population-based cohort study assessed the association of refractive error with the incidence and progression of diabetic retinopathy (DR); 1562 eyes of 860 patients with diabetes and gradable retinal photographs were included. Baseline data was taken between 2004-2009 and follow-up...

British Journal of Ophthalmology cover picture

Efficacy of IVC injection in the treatment of ROP

2 December 2019 | Jonathan Chan | EYE - Vitreo-Retinal

This is a retrospective consecutive case series of patients who received intravitreal conbercept (IVC) as a primary treatment from June 2015 to July 2016 for treatment of retinopathy of prematurity (ROP). Forty-eight eyes of 24 patients were included in the...

Retinoschisis

2 December 2019 | Sofia Rokerya | EYE - Vitreo-Retinal

In this retrospective study the authors evaluate the effect of pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling for lamellar macular hole (LMH) with or without macular retinoschisis in highly myopic eyes. Twenty-one highly myopic patients (22 eyes)...

Intravitreal aflibercept for retinal angiomatous proliferation (RAP)

2 December 2019 | Sofia Rokerya | EYE - Vitreo-Retinal

In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...

Clinical & Experimental Ophthalmology cover picture

Progression of retinitis pigmentosa

2 December 2019 | Ivan Yip | EYE - Vitreo-Retinal

This retrospective study evaluates the rate of progression of retinitis pigmentosa (RP) using multimodal imaging, including spectral-domain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF) and microperimtery (MP). Traditional tests used to evaluate RP, for example, Goldmann visual fields and ERG...

British Journal of Ophthalmology cover

Features of AMD treatment non-responders

1 October 2019 | Jonathan Chan | EYE - Vitreo-Retinal

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

Adjuvant intravitreal dexamethasone implant for persistent CME

1 October 2019 | Sofia Rokerya | EYE - Vitreo-Retinal

In this retrospective, cross-sectional study the authors investigate the efficiency of intravitreal dexamethasone implants (0.7mg) for cystoid macular oedema (CME) persisting, despite immunomodulatory treatment in patients with Behcets’ disease (BD). Twenty-seven eyes of 20 patients (12 males and eight females)...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

1 October 2019 | Sofia Rokerya | EYE - Vitreo-Retinal

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

The global burden of age-related macular degeneration

1 October 2019 | Kurt Spiteri Cornish | EYE - Vitreo-Retinal

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

IOL tilt with air tamponade vs. salt solution

1 October 2019 | Sofia Rokerya | EYE - Vitreo-Retinal

In this study the authors made a comparison of significant postoperative tilt of IOL with air tamponade as opposed to balanced salt solution, in the procedure of combined phaco with IOL and vitrectomy. Thirty-four patients were included into the analysis....

RPE atrophy onset in treated nAMD

1 October 2019 | Sofia Rokerya | EYE - Vitreo-Retinal

In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...

Clinical & Experimental Ophthalmology journal cover

Viral uveitis

1 October 2019 | Ivan Yip | EYE - Vitreo-Retinal

This review covers viral causes of anterior uveitis. A viral aetiology should be suspected when anterior uveitis is accompanied by ocular hypertension, diffuse stellate keratic precipitates or the presence of iris atrophy. Most common viruses associated are herpes simplex, varicella-zoster...

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