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Journal Reviews

Journal of Neuro-Ophthalmology cover image.

Does modern radiological imaging detect lesions associated with internuclear ophthalmoplegia?

30 January 2025 | Lauren R Hepworth | EYE - Neuro-ophthalmology

The authors present a retrospective case review including all patients with a diagnosis of internuclear ophthalmoplegia (INO) presenting to two tertiary neuro-ophthalmology centres over a five-year period. The aim of the study was to assess the sensitivity of modern radiological...

Journal of Neuro-Ophthalmology cover image.

What are the characteristics of patients reporting diplopia in giant cell arteritis?

4 December 2024 | Lauren R Hepworth | EYE - Neuro-ophthalmology

The authors present a retrospective study of individuals diagnosed with giant cell arteritis (GCA) consecutively over a six-year period at a single tertiary ophthalmic centre. The characteristics of binocular diplopia prior to GCA diagnosis was collected from medical records and...

Journal of Neuro-Ophthalmology cover image.

Comparing retinal thickness in Parkinson’s disease, essential tremor and healthy controls

4 December 2024 | Lauren R Hepworth | EYE - Neuro-ophthalmology

This study aimed to compare retinal findings in chronic essential tremor (ET), early Parkinson’s disease (PD) and healthy controls. Those recruited with ET had to have received a diagnosis a minimum of three years previous and those with PD had...

Journal of Neuro-Ophthalmology cover image.

Predicting outcome for visual acuity in optic neuritis associated with multiple sclerosis

3 October 2024 | Lauren R Hepworth | EYE - Neuro-ophthalmology

The authors present a retrospective cohort study to evaluate key predictors of long-term high-contrast visual acuity following optic neuritis associated with multiple sclerosis. All patients coded as optic neuropathy and assessed by a neuro-ophthalmologist over a 10-year period were screened...

Journal of Neuro-Ophthalmology cover image.

Acromegaly associated with enlargement of extraocular recti muscles

3 October 2024 | Lauren R Hepworth | EYE - Neuro-ophthalmology

This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....

Could idebenone by the solution for treating dominant optic atrophy?

3 September 2024 | Claire Howard | EYE - Neuro-ophthalmology

Dominant optic atrophy (DOA) is a disease of the retinal ganglion cells, with no current treatment options. In most cases, DOA is caused by a mutation in the OPA1 gene. The aim of this study was to evaluate the effect...

Longitudinal findings in children with neurofibromatosis type 1

3 September 2024 | Claire Howard | EYE - Neuro-ophthalmology

This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...

Neuro-Ophthalmology journal cover image

Portable vision reading device shows promise for low vision after brain injury

2 August 2024 | Claire Howard | EYE - Neuro-ophthalmology

The authors report a small sample cohort study evaluating the impact of a portable vision reading device (OrCam Read) on vision-related quality-of-life and independent functional status in patients with low vision due to stroke or brain tumours. Six patients with...

Neuro-Ophthalmology journal cover image

Septo-optic dysplasia – a case note review

2 August 2024 | Claire Howard | EYE - Neuro-ophthalmology

Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...

Journal of Neuro-Ophthalmology cover image.

Characteristics of neuro-ophthalmic visual disturbances post-cataract surgery

2 August 2024 | Lauren R Hepworth | EYE - Neuro-ophthalmology

The authors present a retrospective case review of adult patients seen by neuro-ophthalmology over a nine-year period. The aim of the study was to identify the cause of neuro-ophthalmic referrals within six months of cataract surgery. Individuals already known to...

Journal of Neuro-Ophthalmology cover image.

Tumour characteristics influencing visual field outcomes

2 August 2024 | Lauren R Hepworth | EYE - Neuro-ophthalmology

This retrospective study aimed to explore correlations between pituitary tumour characteristics which influenced visual field changes. Cases of transsphenoidal surgery from a six-year period resulting in a pathologic diagnosis of pituitary adenoma from a single centre were identified. Individuals were...

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

1 August 2024 | Claire Howard | EYE - Neuro-ophthalmology

Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...

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