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Image Analysis and Modelling in Ophthalmology

Recent advances have revolutionised ophthalmic imaging and helped understand the pathophysiology of ocular diseases and thus help in the diagnosis and management of ocular diseases. The authors of this book have gone through most of the available imaging techniques available...

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...

DSEK – five year results

This UK based study examined long-term descemet stripping endothelial keratoplasty (DSEK) results, looking at graft survival and endothelial cell losses. Data on 210 grafts were included in analysis. Most frequent indication for DSEK was Fuch’s endothelial dystrophy (81.4%) and 46.3%...

Could the sclera be key to glaucoma?

The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

Combined recession surgery with Bupivacaine injection

The aim of this study was to evaluate the amount of correction of sensory strabismus with Bupivacaine injection combined with antagonist muscle recession. This was a prospective study of nine patients aged 43.5 ±12.3 years; six males and three females....

Cost-effectiveness of femtosecond cataract surgery

Femtosecond laser-assisted cataract surgery has become increasingly popular due to the reported benefits of increasing precision and reproducibility of capsulorrhexis, less power and manipulation required during phacoemulsification, better corneal wound architecture, and the ability to place precise arcuate keratotomy incisions...

Statins inhibit TGFβ2 mediated fibrotic response in astrocytes

Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...

John Weiss offers FREE ‘Remodelling the Cornea & Managing Disease with KERARING Segments’ webinar

John Weiss & Son will be hosting a FREE webinar entitled ‘Remodelling the Cornea & Managing Disease with KERARING Segments’ on 23 September 2021.

How accurate is the supplement content in both generic and branded ophthalmology supplements?

This prospective cross-section study compared the concentrations of Vitamin C, Vitamin E, Zinc, and Copper in five dietary supplements including both national and regional brands used for macular degeneration in the United States. They performed a comparative analysis using gas...

Stromal cell alignment in damaged cornea

Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...