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How to survive the fluorescein round

One of the highlights of the medical retina fellowship programme at Moorfields is the Tuesday morning 8am fluorescein round. It is both exhilarating and terrifying. Exhilarating because they are slick presentations of the most interesting cases that each of the...

Fluorescein angiography and OCT in myopic CNV

Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...

Reliability of Fluorescein Dye Disappearance Test (FDDT)

The authors look at the role of the FDDT in the evaluation of adults with primary acquired nasolacrimal duct obstruction (PANDO) and its correlation with the age and severity of epiphora. They report the results of a prospective cross-sectional comparative...

ZEISS receives FDA clearance for CLARUS 700, enabling high-resolution, ultra-widefield imaging with fluorescein angiography

ZEISS's Medical Technology Segment announced that it has received 510(K) clearance from the FDA for the CLARUS® 700, High-Definition, Ultra-Widefield Imaging system for advanced care specialists. CLARUS 700 is the first high-resolution ultra-widefield imaging with true colour and a complete range of fundus imaging modalities, including fluorescein angiography (FA).

Akimba mice, a model of human diabetic retinopathy

Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...

OCT angiography in PAMM secondary to CRVO

Paracentral acute middle maculopathy (PAMM) is a recently described manifestation presenting with hyperreflective bands within mid retina on spectral domain optical coherence tomography (SD OCT). The current view is that these findings are markers of ischaemia of deep retinal circulation....

Microdroplet and splatter contamination during phacoemulsification in COVID-19 era

Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...

Topical atorvastatin for dry eye and blepharitis

Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...

High-fluence collagen cross-linking

The authors treat seven eyes with progressive keratoconus with a high energy (18mW) for five minutes delivering a total energy similar to that suggested by the original Dresden protocol (3mW for 30mins). All eyes had a thickness >400µm following epithelial...

IVTA use in Behçet’s disease

This study aimed to evaluate the efficacy and safety of intravitreal triamcinolone acetonide (IVTA) injection (4mg/0.1ml) in controlling posterior segment inflammation in patients with Behçet’s disease. Medical records of consecutive patients diagnosed with Behçet’s who underwent IVTA between July 2005...

Retinal pigment epithelium tears

In this paper the authors review the current knowledge of retinal pigment epithelium (RPE) tears. Although rare these can cause loss of visual acuity. They can occur spontaneously in pigment epithelial detachment (PED) due to occult choroidal neovascularisation (CNV), retinal...

Image Analysis and Modelling in Ophthalmology

Recent advances have revolutionised ophthalmic imaging and helped understand the pathophysiology of ocular diseases and thus help in the diagnosis and management of ocular diseases. The authors of this book have gone through most of the available imaging techniques available...