Fluorescein angiography and OCT in myopic CNV
Reviewed by Bheemanagouda Patil

Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are generally not characterised by excessive amounts of exudation, intraretinal oedema or pigment epithelial detachment. This could limit the role of OCT in the management of myopic CNV. This study was thus aimed to evaluate the agreement between FA and SD-OCT in detecting the activity of myopic CNV during bevacizumab treatment. Thirty-four patients with subfoveal myopic CNV were prospectively enrolled. FA and SD-OCT were done at all visits. At baseline, seven eyes showed leakage on FA with no fluid on OCT and one case showed fluid on OCT and no leakage on FA. At month one, 30/34 cases showed complete concordance. They confirmed the key role of FA in diagnosing myopic CNV and reiterated that OCT may assist FA in the management of myopic CNV. 

Fluorescein angiography and spectral-domain optical coherence tomography for monitoring anti-VEGF therapy in myopic choroidal neovascularisation.
Lacono P, Battaglia Parodi M, Papayannis M, et al.
OPHTHALMIC RESEARCH
2014;52(1):25-31.