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Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

Enzymatic clearance of anterior chamber infiltrate in uveitis

Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

The approach to trabeculectomy postoperative complications

Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

Another plant-based remedy for the eye?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Another plant-based remedy for the eye? What do the nicknames Mary Jane, tea, and 420 all...

Exciting opportunities for ophthalmic work in Victoria, Australia – consider moving ‘down under’

Opportunity: We are looking to expand our growing practice of four ophthalmologists.

Understanding and confronting bacterial endophthalmitis

Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...

DISC lens slow myopia progression in Hong Kong Chinese schoolchildren

This is a prospective double-blind randomised trial between September 2007 and October 2009. It included 221 children aged 8-13 years, with myopia between -1 and -5 Dioptres ≤1.00D. There were 111 patients in the defocus incorporated soft contact DISC group...

High myopes with POAG and IOP fluctuations

The authors describe a prospective study of 80 eyes of Chinese patients with primary open-angle glaucoma (POAG) on prostaglandin analogues to investigate if those who also have high myopia exhibit greater short-term intraocular pressure (IOP) fluctuations at resting conditions over...

Fixed or variable Muller’s muscle resection

This is a retrospective analysis of 60 patients who underwent posterior approach ptosis surgery utilising a Muller’s muscle resection. The study compares those who underwent a fixed resection length of 7mm of Muller’s muscle with those having a variable resection...

Surgery for lost inferior rectus muscle

This prospective study evaluated the impact of simultaneous ipsilateral superior rectus (SR) recession and superior rectus (IO) anterior transposition on the primary position alignment in six patients with traumatic loss of the inferior rectus (IR) muscle. Five males and one...

Surgery for myopic esotropia

The authors report a modified Jenson procedure for the treatment of high axial myopic esotropia. Their study includes 15 eyes of 13 patients with a mean age of 50±10.4 years. Mean spherical refraction was -22.53±6.06 dioptres. Mean axial length was...