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2058 results found

Outcomes of plaque radiotherapy for retinoblastoma

The study authors evaluate their experience of plaque radiotherapy for retinoblastoma (RB) in 41 eyes of 41 patients that failed intra-arterial chemotherapy (IAC). This was a retrospective review including 21 females and 20 males. Median age was 18 months and...

Retinoblastoma mortality associations with choroidal and optic nerve invasion

The authors present a retrospective cohort study. Data was extracted from the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) database, based in the US and founded in 1973. Cases of retinoblastoma were extracted using the inclusion criteria of...

Reflections on deployment to ICU

Being unexpectedly uprooted from ophthalmology to ICU during the coronavirus pandemic was certainly a challenge, not just clinically, but emotionally and personally. However, it is only through adversary that we learn to appreciate what we have, and there are definitely...

Platelet rich fibrin membrane for descemetocele

This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...

Advanced vestibular Schwannoma case report

Vestibular Schwannoma is a benign, slow growing tumour which usually presents with unilateral hearing loss. It causes symptoms and findings on ophthalmic examination when the diagnosis is delayed. Ophthalmic findings may be related to the effect of the expanding mass...

MicroRNAs in cataract

In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...

Which factors predispose to pingecula development in a rural Chinese population?

The authors report a cross-sectional study which aimed to determine the prevalence and risk factors for developing pingecula in a rural Chinese population near Shanghai. Nine hundred and fifty-nine persons were recruited from a single village and asked to complete...

Assessing the quality of scars from incisions made by a Colorado needle or a scalpel

Traditional teaching has held the best scars are achieved with cold steel although no previous study has formally investigated this hypothesis in oculoplastic surgery. This paper describes a non-randomised cross-sectional study comparing the scar quality achieved from cold steel with...

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Short-term outcome after intravitreal ranibizumab injections for ROP

This is an interventional case series study of three premature babies (six eyes) with high risk prethreshold or threshold retinopathy of prematurity (ROP) with plus disease that received intravitreal ranibizumab injections for ROP. All infants received intravitreal ranibizumab injections of...

Eye disorders occurring in congenital CMV

The aim of this study was to examine the relationship between congenital cytomegalovirus (CMV) infection and ophthalmological disorders that occur in children and record the frequency and type of eye disorders that occur from the infection. Of 449 potential studies,...

Large vs. small posterior capsulotomy size and visual angle opacification rates

The purpose of this study was to assess the relationship between posterior capsulotomy size and significant visual angle opacification (VAO) in congenital and developmental cataract. This was a retrospective case control of children aged under seven years of age over...