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Acta Ophthalmologica cover image.

Mono vs. multi-therapy in IOP control

1 December 2018 | | EYE - Glaucoma
This randomised control trial studied newly diagnosed glaucoma patients given mono‐ or multi‐therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction. Patients newly diagnosed with manifest primary...
Ophthalmologica journal cover image.

EDOF intraocular lens in eyes with preexisting retinal disease

30 May 2025 | | EYE - Vitreo-Retinal
Extended depth of focus (EDOF) intraocular lens (IOL) offers improved near and intermediate vision, aiming to reduce spectacle dependence in cataract patients. This study aims to evaluate the performance of EDOF lenses following cataract surgery in patients with retinal pathology....
Ophthalmologica journal cover image.

Vascular density evaluated by SS-OCTA and microperimetry in RP

4 August 2025 | | EYE - Vitreo-Retinal
The aim of this retrospective, observational cross-sectional one-year study was to evaluate the retinal and choroidal vessel density in the macular area with swept-source optical coherence tomography angiography (SS-OCTA) in patients of retinitis pigmentosa (RP), to compare this data with...
Experimental Eye Research cover image.

Autophagy in lens mitochondria loss

1 April 2014 | | EYE - Cataract, EYE - Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Managing a patient with ptosis

1 August 2015 | | EYE - Oculoplastic, EYE - Orbit
A 50-year-old male patient is referred from the Accident & Emergency department with a history of ptosis. How will you manage this patient? Mr Bertie Fernando Clinical management Clinical management starts with a sound clinical history. Current history The history...

Optometrist found guilty of manslaughter

1 December 2016 | EYE - General
To start our new Optometry section, editor Janet Pooley takes a look at the tragic death of Vincent Barker and asks what lessons can be learned. In August, Optometrist Honey Rose was found guilty of the manslaughter of eight-year-old Vincent...

RNIB's verdict on the 10-Year Plan for the NHS

4 July 2025 | news, charity, 10 Year Health Plan, NHS, government
The UK Government has released the long awaited 10-Year Plan to reform the National Health Service (NHS) in England. The Plan outlines the details and proposals to deliver on the promised three changes which would transform healthcare across the country:...

The results of the last survey Oct24

3 October 2024 | | EYE - Glaucoma
*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. The sample...

Lockdown and eye health – a case of accommodative spasm

6 April 2021 | | EYE - Orbit, EYE - Imaging, EYE - General
A 25-year-old male presented to the eye casualty with a one-day history of sudden onset worsening vision. More specifically, he noted his vision was more blurred than usual and this was more exaggerated for near-work than for distance-work. He was...

How to pass the FRCOphth part 2 oral exam

1 June 2022 | | EYE - General
If you have got this far in terms of your exams, relax. In terms of pass rate, the hardest FRCOphth membership exams are already behind you. The pass mark for the part 2 oral exam is around 75%, and about...

Isolated trochlear (fourth cranial) nerve palsy in an Asian population

1 August 2018 | | EYE - Neuro-ophthalmology
The authors report on 35 consecutive new cases of isolated fourth cranial nerve palsy seen over a period of six months in one neuro-ophthalmology clinic in Southeast Asia, with emphasis on their aetiology and management. We report on 35 patients...

How to be ‘appy’ on call: a brief guide to mobile phone applications for the on-call ophthalmologist

1 December 2022 | | EYE - General
One of the unexpected outcomes of the COVID-19 pandemic has been an increased reliance and integration of computer technology within hospital medicine. The need for stricter infection control policies during and after lockdown has seen a boom in technology utilisation....